M
Maria A. Rocca
Researcher at Vita-Salute San Raffaele University
Publications - 647
Citations - 29881
Maria A. Rocca is an academic researcher from Vita-Salute San Raffaele University. The author has contributed to research in topics: Multiple sclerosis & Magnetic resonance imaging. The author has an hindex of 83, co-authored 556 publications receiving 25283 citations. Previous affiliations of Maria A. Rocca include University at Buffalo & Katholieke Universiteit Leuven.
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Journal ArticleDOI
Adaptive functional changes in the cerebral cortex of patients with nondisabling multiple sclerosis correlate with the extent of brain structural damage
TL;DR: This study shows that cortical activation occurs over a rather distributed sensorimotor network in nondisabled relapsing‐remitting multiple sclerosis patients, and suggests that increased recruitment of this cortical network contributes to the limitation of the functional impact of white matter multiple sclerosis injury.
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A method for obtaining tract-specific diffusion tensor MRI measurements in the presence of disease: application to patients with clinically isolated syndromes suggestive of multiple sclerosis.
TL;DR: In CIS patients with clinical symptoms related to motor function, the DT-derived mean diffusivity and the lesion volume in the PYT were found to be increased, while the fractional anisotropy was no different, when compared to those patients without motor symptoms.
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Assessment of system dysfunction in the brain through MRI-based connectomics.
Massimo Filippi,Martin P van den Heuvel,Alex Fornito,Yong He,Hilleke E. Hulshoff Pol,Federica Agosta,Giancarlo Comi,Maria A. Rocca +7 more
TL;DR: Network-based analysis of structural and functional connections has provided a new technique to study the brains of healthy people and patients with neurological and psychiatric disorders and improved understanding of the clinical manifestations noted in these patients, including disability and cognitive impairment.
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Pathologic damage in MS assessed by diffusion-weighted and magnetization transfer MRI.
TL;DR: DWI detects severe tissue disruption inside lesions and subtle widespread abnormalities in NAWM in patients with relapsing-remitting MS and MT and DWI may provide information about different aspects of brain pathology in MS.
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Multiple sclerosis: effects of cognitive rehabilitation on structural and functional MR imaging measures--an explorative study.
Massimo Filippi,Gianna C Riccitelli,Flavia Mattioli,Ruggero Capra,Chiara Stampatori,Elisabetta Pagani,Paola Valsasina,Massimiliano Copetti,Andrea Falini,Giancarlo Comi,Maria A. Rocca +10 more
TL;DR: Rehabilitation of attention and information processing and executive functions in RR MS may be effected through enhanced recruitment of brain networks subserving the trained functions, as compared with their performance at baseline.