M
María Angeles Lima
Researcher at Médecins Sans Frontières
Publications - 15
Citations - 663
María Angeles Lima is an academic researcher from Médecins Sans Frontières. The author has contributed to research in topics: Visceral leishmaniasis & Leishmaniasis. The author has an hindex of 13, co-authored 15 publications receiving 593 citations.
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Journal ArticleDOI
Liposomal amphotericin B as a treatment for human leishmaniasis
Manica Balasegaram,Koert Ritmeijer,María Angeles Lima,Sakib Burza,Gemma Ortiz Genovese,Barbara Milani,Sara Gaspani,Julien Potet,François Chappuis +8 more
TL;DR: A review of clinical studies on LAMB for VL and other forms of leishmaniasis is provided, finding it to be highly efficacious and safe in over 8000 VL patients treated by MÉdecins Sans Frontières in South Asia, and its use was feasible even at primary healthcare level.
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Five-Year Field Results and Long-Term Effectiveness of 20 mg/kg Liposomal Amphotericin B (Ambisome) for Visceral Leishmaniasis in Bihar, India
Sakib Burza,Prabhat K. Sinha,Raman Mahajan,María Angeles Lima,Gaurab Mitra,Neena Verma,Manica Balasegarem,Pradeep Das +7 more
TL;DR: This is the largest cohort of VL patients treated with 20 mg/kg Ambisome worldwide and has high initial and long-term efficacy, and a low rate of adverse reactions when administered under field conditions in Bihar, India.
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Natural history of a visceral leishmaniasis outbreak in highland Ethiopia.
Mercè Herrero,Giannos Orfanos,Daniel Argaw,Abate Mulugeta,Pilar Aparicio,Fernando Parreño,Oscar Bernal,Daniel Rubens,Jaime Pedraza,María Angeles Lima,Laurence Flevaud,Pedro Pablo Palma,Seife Bashaye,Jorge Alvar,Caryn Bern +14 more
TL;DR: The VL epidemic expanded rapidly over a several-year period, culminating in an epidemic peak in the last third of 2005, spread over two districts, and transformed into a sustained endemic situation by 2007.
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Visceral Leishmaniasis and HIV Co-infection in Bihar, India: Long-term Effectiveness and Treatment Outcomes with Liposomal Amphotericin B (AmBisome)
Sakib Burza,Raman Mahajan,Prabhat K. Sinha,Johan van Griensven,Krishna Pandey,María Angeles Lima,Marta Gonzalez Sanz,Temmy Sunyoto,Sunil Kumar,Gaurab Mitra,Ranjeet Kumar,Neena Verma,Pradeep Das +12 more
TL;DR: Even after initial cure following treatment with AmBisome, these patients appear to have much higher rates of VL relapse and mortality than patients not known to be HIV-positive, although relapse rates appear to stabilize after 2 years.
Journal ArticleDOI
Who is a typical patient with visceral leishmaniasis? Characterizing the demographic and nutritional profile of patients in Brazil, East Africa, and South Asia.
Michael O. Harhay,Piero Olliaro,Michel Vaillant,François Chappuis,María Angeles Lima,Koert Ritmeijer,Carlos Henrique Nery Costa,Dorcas Lamounier Costa,Suman Rijal,Shyam Sundar,Manica Balasegaram +10 more
TL;DR: In this paper, the authors present information about the age, gender, weight, and height of 29,570 consecutive leishmaniasis patients presenting to 20 locations in six geographic endemic regions of Brazil, East Africa, Nepal, and India between 1997 and 2009.