M
Maria Gregori
Researcher at University of Milano-Bicocca
Publications - 34
Citations - 1472
Maria Gregori is an academic researcher from University of Milano-Bicocca. The author has contributed to research in topics: P3 peptide & Liposome. The author has an hindex of 19, co-authored 34 publications receiving 1269 citations. Previous affiliations of Maria Gregori include University of Milan.
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Journal ArticleDOI
Lipid-based nanoparticles with high binding affinity for amyloid-β1–42 peptide
Marco Gobbi,Francesca Re,Mara Canovi,Marten Beeg,Maria Gregori,Silvia Sesana,Sandro Sonnino,Doriano Brogioli,C Musicanti,P Gasco,Mario Salmona,Massimo Masserini +11 more
TL;DR: The PA/CL NPs described in this work are endowed with the highest affinity for Abeta so far reported, which makes them a very promising vector for the targeted delivery of potential new diagnostic and therapeutic molecules to be tested in appropriate animal models.
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Functionalization of liposomes with ApoE-derived peptides at different density affects cellular uptake and drug transport across a blood-brain barrier model
Francesca Re,Ilaria Cambianica,Cristiano Zona,Silvia Sesana,Maria Gregori,Roberta Rigolio,Barbara La Ferla,Francesco Nicotra,Gianluigi Forloni,Alfredo Cagnotto,Mario Salmona,Massimo Masserini,Giulio Sancini +12 more
TL;DR: These NLs appear particularly suitable for implementing further strategies for drug brain targeting, and the ability of ApoE-NLs to enhance the transport of a drug payload through a RBE4 cell monolayer is studied.
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Nanotechnology for neurodegenerative disorders
TL;DR: This review focuses on the state-of-the-art of nanomaterials suitable for therapy and diagnostic imaging of the most common neurodegenerative disorders, as well as for neuroprotection and neuronal tissue regeneration.
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Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide.
Mark Taylor,Susan Moore,Spyridon Mourtas,Anna Niarakis,Francesca Re,Cristiano Zona,Barbara La Ferla,Francesco Nicotra,Massimo Masserini,Sophia G. Antimisiaris,Maria Gregori,David Allsop +11 more
TL;DR: Of the three forms of curcumin liposomes tested, the click-curcumin type was by far the most effective and could be further developed as a novel treatment for Alzheimer's disease.
Journal ArticleDOI
Liposomes functionalized to overcome the blood–brain barrier and to target amyloid-β peptide: the chemical design affects the permeability across an in vitro model
Elisa Salvati,Francesca Re,Silvia Sesana,Ilaria Cambianica,Giulio Sancini,Massimo Masserini,Maria Gregori +6 more
TL;DR: For the first time, it is proved herein the superior efficiency of covalent coupling of RI7217 versus biotin/streptavidin ligation to facilitate liposomes in overcoming the BBB in vitro.