M
María José Alcaraz
Researcher at Polytechnic University of Valencia
Publications - 110
Citations - 11331
María José Alcaraz is an academic researcher from Polytechnic University of Valencia. The author has contributed to research in topics: Inflammation & Heme oxygenase. The author has an hindex of 42, co-authored 108 publications receiving 7787 citations. Previous affiliations of María José Alcaraz include University of Valencia & ARCO.
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Journal ArticleDOI
Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes.
Julia Platas,Maria Isabel Guillén,María Dolores Pérez del Caz,Francisco Gomar,Miguel Angel Castejón,Vicente Mirabet,María José Alcaraz +6 more
TL;DR: In this paper, the authors investigated whether the conditioned medium from adipose-derived mesenchymal stem cells may regulate senescence features induced by inflammatory stress in OA chondrocytes.
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Study of the antioedema activity of some seaweed and sponge extracts from the mediterranean coast in mice
Miguel Payá,María Luisa Ferrándiz,Maria-Jesus Sanz,G. Bustos,Rafael Blasco,José Luis Ríos,María José Alcaraz +6 more
TL;DR: The most interesting seaweed extracts were found to be from Corallina elongata, Galaxaura oblongata, Laurencia obtusa and Udotea petiolata, where both extracts of each species induced a large antioedema effect in both models employed.
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The CO-releasing molecule CORM-2 is a novel regulator of the inflammatory process in osteoarthritic chondrocytes
TL;DR: These data have opened new mechanisms of action for CORM-2, raising the prospect that CO-releasing molecules are an interesting strategy for the development of new treatments in articular conditions.
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6-Dimethylamino 1H-Pyrazolo[3,4-d]pyrimidine derivatives as new inhibitors of inflammatory mediators in intact cells
José M. Quintela,Carlos Peinador,L. Gonzalez,Isabel Devesa,M.Luisa Ferrándiz,María José Alcaraz,Ricardo Riguera +6 more
TL;DR: The synthesis of 6-dimethylamino 1H-pyrazolo[3,4-d]pyrimidines substituted at positions 1 and 4, and their effects on murine macrophage and human neutrophil functions are described.
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Extracellular Vesicles from Mesenchymal Stem Cells as Novel Treatments for Musculoskeletal Diseases.
TL;DR: The current understanding of MSC EVs actions in preclinical studies of immune regulation and rheumatoid arthritis, bone repair and bone diseases, cartilage repair and osteoarthritis, intervertebral disk degeneration and skeletal muscle and tendon repair is summarized.