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Maria Laura Bellone
Researcher at University of Salerno
Publications - 5
Citations - 54
Maria Laura Bellone is an academic researcher from University of Salerno. The author has contributed to research in topics: Small molecule & Virus. The author has an hindex of 2, co-authored 5 publications receiving 6 citations.
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Journal ArticleDOI
Interactions with Microbial Proteins Driving the Antibacterial Activity of Flavonoids.
Giuliana Donadio,Francesca Mensitieri,Valentina Santoro,Valentina Parisi,Maria Laura Bellone,Nunziatina De Tommasi,Viviana Izzo,Fabrizio Dal Piaz +7 more
TL;DR: In this article, the authors present an overview of the most interesting results obtained in the research focused on the study of the interactions between flavonoids and bacterial proteins, which demonstrate the great potential of these compounds in developing innovative systems, which can help address the increasingly serious problem of antibiotic resistance.
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Production in Escherichia coli of recombinant COVID-19 spike protein fragments fused to CRM197.
Maria Laura Bellone,Andrea Puglisi,Fabrizio Dal Piaz,Alejandro Hochkoeppler,Alejandro Hochkoeppler +4 more
TL;DR: In this paper, the authors show that the RBD of COVID-19 spike protein can be easily produced in Escherichia coli when fused to a fragment of CRM197, a variant of diphtheria toxin currently used for a number of conjugated vaccines.
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Limonoids from Guarea guidonia and Cedrela odorata : Heat Shock Protein 90 (Hsp90) Modulator Properties of Chisomicine D.
Maria Laura Bellone,César Muñoz Camero,Maria Giovanna Chini,Fabrizio Dal Piaz,Vanessa Hernandez,Giuseppe Bifulco,Nunziatina De Tommasi,Alessandra Braca +7 more
TL;DR: In this paper, nine new limonoids (1-9) were isolated from the stem bark of Guarea guidonia and Cedrela odorata, and their structures were elucidated using 1D and 2D NMR and MS data and chemical methods.
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Backbone chemical shift spectral assignments of SARS coronavirus-2 non-structural protein nsp9.
Erika F. Dudás,Rita Puglisi,Sophie Marianne Korn,Caterina Alfano,Maria Laura Bellone,Fabrizio Dal Piaz,Geoff Kelly,Elisa Monaca,Andreas Schlundt,Harald Schwalbe,Annalisa Pastore +10 more
TL;DR: In this paper, the backbone atoms of the SARS-CoV-2 protein nsp9 have been assigned to the backbone of ORF1a, which is encoded by ORF 1a and seems to be essential for RNA synthesis.
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The plant diterpene epoxysiderol targets Hsp70 in cancer cells, affecting its ATPase activity and reducing its translocation to plasma membrane.
Lorenzo Fiengo,Gianluigi Lauro,Maria Laura Bellone,Giuseppe Bifulco,F. Dal Piaz,N. De Tommasi +5 more
TL;DR: In this paper, the ATP-dependent molecular chaperone Hsp70 is over-expressed in cancer cells where it plays pivotal roles in stabilization of onco-proteins, promoting cell proliferation and protecting cells from apoptosis and necrosis.