M
María Sereno
Researcher at Sofia University
Publications - 66
Citations - 1212
María Sereno is an academic researcher from Sofia University. The author has contributed to research in topics: Cancer & Lung cancer. The author has an hindex of 18, co-authored 59 publications receiving 944 citations. Previous affiliations of María Sereno include Hospital Universitario La Paz & Autonomous University of Madrid.
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Journal ArticleDOI
Implications of oxidative stress and cell membrane lipid peroxidation in human cancer (Spain).
Paloma Cejas,Enrique Casado,Cristobal Belda-Iniesta,Javier de Castro,Enrique Espinosa,Andrés Redondo,María Sereno,Miguel Ángel García-Cabezas,Juan Ángel Fresno Vara,Aurora Domínguez-Cáceres,Rosario Perona,Manuel González-Barón +11 more
TL;DR: The relevance of oxidative stress, particularly of lipid peroxidation, in cell response with special focus in carcinogenesis and cancer therapy is reviewed that suggests PH-GPx as a potentially important enzyme involved in the control of this processes.
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Chemotherapy-induced peripheral neuropathy: clinical features, diagnosis, prevention and treatment strategies
Gerardo Gutiérrez-Gutiérrez,María Sereno,Ambrosio Miralles,Enrique Casado-Sáenz,Eduardo Gutiérrez-Rivas +4 more
TL;DR: An approach to the diagnosis of these disorders is suggested and an update on new therapies is provided to help reduce the burden of this complication.
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Lipid metabolism and lung cancer.
María Merino Salvador,Marta Gómez de Cedrón,Juan Moreno Rubio,Juan Moreno Rubio,Sandra Falagán Martínez,Ruth Sánchez Martínez,Enrique Casado,Ana Ramírez de Molina,María Sereno +8 more
TL;DR: The basis of lipid metabolism in lung cancer is reviewed, potential biomarkers are suggested, and potential therapeutic agents based on bioactive compounds such as cerulenin, SCD1, ACLY inhibitors, statins, polyphenolic compounds, etc.
Journal ArticleDOI
Cardiac toxicity: old and new issues in anti-cancer drugs
María Sereno,Antonella Brunello,Alberto Chiappori,Jorge Barriuso,Enrique Casado,Cristóbal Belda,Javier de Castro,Jaime Feliu,Manuel González-Barón +8 more
TL;DR: An exhaustive review of the cardiovascular side effects associated to new anticancer drugs, from new formulations of anthracyclines to tyrosine kinase inhibitors and monoclonal antibodies is presented.
Journal ArticleDOI
Whole-exome sequencing reveals defective CYP3A4 variants predictive of paclitaxel dose-limiting neuropathy
María Apellániz-Ruiz,Mi-Young Lee,Lara Sánchez-Barroso,Gerardo Gutiérrez-Gutiérrez,Isabel Calvo,Laura García-Estévez,María Sereno,Jesús García-Donas,Beatriz Castelo,Eva Guerra,Luis J Leandro-García,Alberto Cascón,Inger Johansson,Mercedes Robledo,Magnus Ingelman-Sundberg,Cristina Rodríguez-Antona +15 more
TL;DR: YP3A4 defective variants may provide a basis for paclitaxel treatment individualization and be the first description of a genetic marker associated with paclitrixel treatment modifications caused by neuropathy.