M
Marta Gómez de Cedrón
Researcher at IMDEA
Publications - 41
Citations - 1287
Marta Gómez de Cedrón is an academic researcher from IMDEA. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 11, co-authored 33 publications receiving 1005 citations.
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Journal ArticleDOI
Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression
Maria J. Bueno,Ignacio Pérez de Castro,Marta Gómez de Cedrón,Javier Santos,George A. Calin,Juan C. Cigudosa,Carlo M. Croce,José Fernández-Piqueras,Marcos Malumbres +8 more
TL;DR: It is reported that a fragile chromosomal region lost in specific hematopoietic malignancies, miR-203, functions as a tumor suppressor, and re-expression of this microRNA might have therapeutic benefits in specifichematopOieticmalignancies.
Journal ArticleDOI
Multiple E2F-Induced MicroRNAs Prevent Replicative Stress in Response to Mitogenic Signaling
Maria J. Bueno,Marta Gómez de Cedrón,Usua Laresgoiti,José Fernández-Piqueras,Ana M. Zubiaga,Marcos Malumbres +5 more
TL;DR: E2F-induced miRNAs contribute to limiting the cellular responses to E2F activation, thus preventing replicative stress and play multiple roles in cell proliferation and in proliferative diseases such as cancer.
Journal ArticleDOI
A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy
Ruth Sánchez-Martínez,Silvia Cruz-Gil,Marta Gómez de Cedrón,Mónica Álvarez-Fernández,Teodoro Vargas,Susana Molina,Belén García,Jesús Herranz,Juan Moreno-Rubio,Juan Moreno-Rubio,Guillermo Reglero,Mirna Perez-Moreno,Jaime Feliu,Marcos Malumbres,Ana Ramírez de Molina +14 more
TL;DR: A metabolic acyl-CoA synthetase/stearoyl- CoA desaturase ACSL/SCD network causing an epithelial-mesenchymal transition (EMT) program that promotes migration and invasion of colon cancer cells, and might represent a new therapeutic opportunity for colon cancer treatment.
Journal ArticleDOI
Lipid metabolism and lung cancer.
María Merino Salvador,Marta Gómez de Cedrón,Juan Moreno Rubio,Juan Moreno Rubio,Sandra Falagán Martínez,Ruth Sánchez Martínez,Enrique Casado,Ana Ramírez de Molina,María Sereno +8 more
TL;DR: The basis of lipid metabolism in lung cancer is reviewed, potential biomarkers are suggested, and potential therapeutic agents based on bioactive compounds such as cerulenin, SCD1, ACLY inhibitors, statins, polyphenolic compounds, etc.
Journal ArticleDOI
Alterations of Lipid Metabolism in Cancer: Implications in Prognosis and Treatment.
TL;DR: The impact of obesity and related tumor microenviroment alterations as modifiable risk factors in cancer is analyzed, focusing on the lipid alterations co-occurring during tumorigenesis, and the value of precision technologies and its application to target lipid metabolism in cancer are discussed.