Maria Teresa de Seixas Alves

TL;DR: The overall 5- and 10-year survival rates were lower than the rates reported in North American and European trials and a pattern of advanced disease at diagnosis was often present, with a high proportion of patients having metastases and large tumor size.

TL;DR: The mortality risk increased with older age, presence of metastatic disease at diagnosis, development of local recurrence when the patient was first seen, use of amputation instead of limb salvage/wide resection, employment of unusual treatments,Use of chemotherapeutic regimens other than anthracycline and platinum and use of methotrexate.

TL;DR: Low-intensity laser therapy appears to reduce the severity of mucositis, at least in part, by reducing COX-2 levels and associated inhibition of the inflammatory response.

TL;DR: The aim of this study was to investigate the mechanisms of action of LLLT on chemotherapy‐induced oral mucositis, as related to effects on collagen expression and inflammation.