M
Marianne E. Buck
Researcher at Yale University
Publications - 2
Citations - 1479
Marianne E. Buck is an academic researcher from Yale University. The author has contributed to research in topics: Potassium channel & Calcium-activated potassium channel. The author has an hindex of 2, co-authored 2 publications receiving 1452 citations.
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Journal ArticleDOI
MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia
Geoffrey W. Abbott,Federico Sesti,Igor Splawski,Marianne E. Buck,Michael H. Lehmann,Katherine W Timothy,Mark T. Keating,Steve A.N. Goldstein +7 more
TL;DR: A mechanism for acquired arrhythmia is revealed: genetically based reduction in potassium currents that remains clinically silent until combined with additional stressors.
Journal ArticleDOI
Proton Block and Voltage Gating Are Potassium-dependent in the Cardiac Leak Channel Kcnk3
Coeli M. Lopes,Patrick G. Gallagher,Marianne E. Buck,Margaret H. Butler,Steve A.N. Goldstein +4 more
TL;DR: The genomic structure, cardiac localization, and biophysical properties of a murine example are considered, and single Kcnk3 channels open across the physiological voltage range; hence they are “leak” conductances.