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Marie Brázdová

Researcher at Academy of Sciences of the Czech Republic

Publications -  42
Citations -  981

Marie Brázdová is an academic researcher from Academy of Sciences of the Czech Republic. The author has contributed to research in topics: DNA & DNA supercoil. The author has an hindex of 19, co-authored 42 publications receiving 913 citations. Previous affiliations of Marie Brázdová include Heinrich Pette Institute & University of Veterinary and Pharmaceutical Sciences Brno.

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Journal ArticleDOI

Application of avidin-biotin technology and adsorptive transfer stripping square-wave voltammetry for detection of DNA hybridization and avidin in transgenic avidin maize.

Michal Masarik, +8 more
- 01 Jun 2003 - 
TL;DR: The results demonstrated that streptavidin/avidin AdTS SWV is a sensitive and specific method for quantifying DNA and proteins in biological samples such as foods and tissue extracts, including genetically modified crops and other plants in neighboring fields.
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Vinylsulfonamide and Acrylamide Modification of DNA for Cross-linking with Proteins†

Jitka Dadová, +8 more
- 27 Sep 2013 - 
TL;DR: Bioorthogonal covalent cross-linking of DNA-binding proteins (p53) to DNA was achieved through novel DNA probes bearing a reactive vinylsulfonamide (VS) group that served as building block for polymerase synthesis of modified DNA.
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Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity

Timo Quante, +5 more
- 01 Sep 2012 - 
TL;DR: It is found that mutp53 preferentially and autonomously binds to G/C-rich DNA around transcription start sites (TSS) of many genes characterized by active chromatin marks and frequently associated with transcription-competent RNA polymerase II.
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Effect of transition metals on binding of p53 protein to supercoiled DNA and to consensus sequence in DNA fragments.

Emil Paleček, +5 more
- 17 Jun 1999 - 
TL;DR: Modulation of binding of p53 to DNA by physiological concentrations of zinc might represent a novel pathway that regulates p53 activity in vivo.
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Modulation of gene expression in U251 glioblastoma cells by binding of mutant p53 R273H to intronic and intergenic sequences

Marie Brázdová, +8 more
- 01 Apr 2009 - 
TL;DR: A model is proposed that attributes the oncogenic functions of mutp53 to its ability to interact with intronic and intergenic non-B DNA sequences and modulate gene transcription via re-organization of chromatin.