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Marie-Francoise Doursout

Researcher at University of Texas Health Science Center at Houston

Publications -  56
Citations -  1370

Marie-Francoise Doursout is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Hemodynamics & Cardiac output. The author has an hindex of 18, co-authored 52 publications receiving 1239 citations. Previous affiliations of Marie-Francoise Doursout include University of Texas at Austin.

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Vascular system: role of nitric oxide in cardiovascular diseases.

TL;DR: NO has also been implicated in the pathology of many inflammatory diseases, including arthritis, myocarditis, colitis, and nephritis and a large number of pathologic conditions such as amyotrophic lateral sclerosis, cancer, diabetes, and neurodegenerative diseases.
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Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw.

TL;DR: Both in vitro and in vivo studies show that FFP has beneficial effects on endothelial permeability, vascular stability, and resuscitation in rats after HS, and the benefits are independent of hemostasis and diminish between days 0 and 5 of storage.
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Comparison of the effects of isoflurane and desflurane on cardiovascular dynamics and regional blood flow in the chronically instrumented dog.

TL;DR: Seven mongrel dogs were chronically instrumented for the measurement of aortic and left ventricular blood pressures, cardiac output,left ventricular wall thickening, left Ventricular dP/dt, and circumflex coronary, renal, hepatic and portal blood flows under the influence of desflurane and isoflurane.
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Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock.

TL;DR: In this paper, in vitro studies with pulmonary endothelial cells (PECs) reveal that conditioned media from MSCs and MSC-PEC co-cultures inhibits PEC permeability by preserving adherens junctions, suggesting that M SCs, acting directly and through soluble factors, are potent stabilizers of the vascular endothelium and inflammation.
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Effects of sevoflurane and isoflurane on hepatic circulation in the chronically instrumented dog.

TL;DR: Both anesthetics led to similar systemic and hepatic vasodilation and neither anesthetic significantly changed renal blood flow.