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Yanna Cao
Researcher at University of Texas Health Science Center at Houston
Publications - 43
Citations - 1427
Yanna Cao is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Transforming growth factor beta & Transforming growth factor. The author has an hindex of 18, co-authored 42 publications receiving 1283 citations. Previous affiliations of Yanna Cao include University of Texas Medical Branch & University of Manitoba.
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Journal ArticleDOI
Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β-induced apoptosis
TL;DR: It is reported that the sensitivity to TGF-β-induced apoptosis is regulated by crosstalk between the Akt/PKB serine/threonine kinase and Smad3 through a mechanism that is independent of Akt kinase activity.
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Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw.
Shibani Pati,Nena Matijevic,Marie-Francoise Doursout,Tien C. Ko,Yanna Cao,Xiyun Deng,Rosemary A. Kozar,Elizabeth Hartwell,Jodie L. Conyers,John B. Holcomb +9 more
TL;DR: Both in vitro and in vivo studies show that FFP has beneficial effects on endothelial permeability, vascular stability, and resuscitation in rats after HS, and the benefits are independent of hemostasis and diminish between days 0 and 5 of storage.
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Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1.
Tamara Alliston,Tien C. Ko,Tien C. Ko,Yanna Cao,Yao Yun Liang,Xin-Hua Feng,Chenbei Chang,Rik Derynck +7 more
TL;DR: Evi-1 acts as a general Smad corepressor to inhibit TGF-β-, activin-, and BMP-inducible transcription, suggesting a role of repression of BMP and activin signals by Evi-1 in vertebrate embryogenesis.
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Macrophage bone morphogenic protein receptor 2 depletion in idiopathic pulmonary fibrosis and Group III pulmonary hypertension
Ning Yuan Chen,Scott D. Collum,Fayong Luo,Tingting Weng,Thuy T. Le,Adriana M. Hernandez,Kemly Philip,Jose G. Molina,Luis J. Garcia-Morales,Yanna Cao,Tien C. Ko,Javier Amione-Guerra,Odeaa Al-Jabbari,R.R. Bunge,Keith A. Youker,Brian A. Bruckner,Rizwan Hamid,Jonathan Davies,Neeraj Sinha,Harry Karmouty-Quintana +19 more
TL;DR: The data suggest that depletion of BMPR2 mediated by a collection of miRs induced by IL6 and subsequent STAT3 phosphorylation as a novel mechanism participating to fibroproliferative and vascular injuries in IPF.
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BMP2 inhibits TGF-β-induced pancreatic stellate cell activation and extracellular matrix formation
Xuxia Gao,Yanna Cao,Yanna Cao,Wenli Yang,Chaojun Duan,Judith F. Aronson,Christiana Rastellini,Celia Chao,Mark R. Hellmich,Tien C. Ko,Tien C. Ko +10 more
TL;DR: Investigating the potential anti-fibrogenic role of BMPs in the pancreas using an in vivo CP model and an in vitro PSC model found that BMP2 opposes the fibrogenic function of TGF-β in PSCs through the Smad1 signaling pathway.