Marie-Laure Kürzinger

TL;DR: The results clearly suggest that broad-ranging statistical signal detection in Twitter and Facebook, using currently available methods for adverse event recognition, performs poorly and cannot be recommended at the expense of other pharmacovigilance activities.

TL;DR: Maternal exposure to intranasal triamcinolone during pregnancy was not associated with the risk of SGA/spontaneous abortions/overall malformations, however, it has been shown to increase therisk of respiratory system defects.

TL;DR: The overall performance of SDRs detected from patients’ medical forums in France showed that data from medical forums may be a valuable source for signal detection, and performance against established signals was good.

TL;DR: This article considers published quantitative benefit–risk evaluations which may have informed health care professionals and/ or payor as well as contributed to decision making purposes in the regulatory setting for drug, vaccine and/or device approval.

TL;DR: Two web query methods have moderate sensitivity in detecting signals in web query data compared with reference SDAs in FAERS, but the query metrics generate many false-positives and have low specificity compared withReference signal-detection algorithms commonly used with the FDA AE Reporting System (FAERS) database.