M
Marie Piette
Researcher at University of Liège
Publications - 13
Citations - 322
Marie Piette is an academic researcher from University of Liège. The author has contributed to research in topics: Liposome & Cyclodextrin. The author has an hindex of 7, co-authored 13 publications receiving 299 citations. Previous affiliations of Marie Piette include Université libre de Bruxelles.
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Journal ArticleDOI
Betamethasone-in-cyclodextrin-in-liposome: The effect of cyclodextrins on encapsulation efficiency and release kinetics
TL;DR: It is shown that release kinetics are directly correlated with encapsulation efficiency, which is closely related to betamethasone concentration in cyclodextrin complex solution, which was proved by the comparison of phase solubility diagrams of both betamETHasone and cholesterol.
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Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives.
Marie Laure Volvert,Sandrine Seyen,Marie Piette,Brigitte Evrard,Marjorie Gangolf,Jean Christophe Plumier,Lucien Bettendorff +6 more
TL;DR: Benfotiamine, an S-acyl derivative practically insoluble in organic solvents, should be differentiated from truly lipid-soluble thiamine disulfide derivatives with a different mechanism of absorption and different pharmacological properties, which would explain why beneficial effects of benfutiamine have only been observed in peripheral tissues.
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Study of the relationship between lipid binding properties of cyclodextrins and their effect on the integrity of liposomes.
TL;DR: It was shown that the observed effect on calcein release can be directly related to the affinity of cyclodextrins for both lipid components of liposomes, cholesterol and phosphatidylcholine.
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Mucoadhesive cellulosic derivative sponges as drug delivery system for vaginal application
TL;DR: The aim of this study was to formulate and to characterize a solid system, called sponges, obtained by lyophilization of cellulosic derivative (HEC 250M) hydrogels, considered as potential drug delivery systems intended for vaginal application.
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Pharmacokinetic study of a new synthetic MMP inhibitor (Ro 28-2653) after IV and oral administration of cyclodextrin solutions.
Marie Piette,Brigitte Evrard,Francis Frankenne,Patrice Chiap,Pascal Bertholet,Delphine Castagne,Jean-Michel Foidart,Luc Delattre,Géraldine Piel +8 more
TL;DR: An increase in Ro 28-2653 solubility, via ternary complex formation, can lead to an increase in the oral bioavailability of this drug, and a synergistic effect exists between hydroxypropyl-beta-cyclodextrin (HP- beta-CD) and l-lysine.