M
Marie-Thérèse Nugeyre
Researcher at Pasteur Institute
Publications - 53
Citations - 10032
Marie-Thérèse Nugeyre is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Virus & Viral replication. The author has an hindex of 25, co-authored 52 publications receiving 9758 citations. Previous affiliations of Marie-Thérèse Nugeyre include University of Paris-Sud & Université Paris-Saclay.
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Journal ArticleDOI
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).
Françoise Barré-Sinoussi,J. C. Chermann,Félix A. Rey,Marie-Thérèse Nugeyre,S. Chamaret,Jacqueline Gruest,Charles Dauguet,Claudine Axler-Blin,F. Vézinet-Brun,Christine Rouzioux,Willy Rozenbaum,Luc Montagnier +11 more
TL;DR: From these studies it is concluded that this virus as well as the previous HTLV isolates belong to a general family of T-lymphotropic retroviruses that are horizontally transmitted in humans and may be involved in several pathological syndromes, including AIDS.
Journal ArticleDOI
Selective tropism of lymphadenopathy associated virus (LAV) for helper-inducer T lymphocytes.
David Klatzmann,Françoise Barré-Sinoussi,Marie-Thérèse Nugeyre,C Danquet,E Vilmer,C Griscelli,F Brun-Veziret,C. Rouzioux,Jean Claude Gluckman,J.C. Chermann +9 more
TL;DR: Virus production was associated with impaired proliferation, modulation of T3-T4 cell markers, and the appearance of cytopathic effects, providing evidence for the involvement of LAV in AIDS.
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Adaptation of Lymphadenopathy Associated Virus (LAV) to Replication in EBV-Transformed B Lymphoblastoid Cell Lines
Luc Montagnier,Jacqueline Gruest,S. Chamaret,Charles Dauguet,C. Axler,Denise Guetard,Marie-Thérèse Nugeyre,Françoise Barré-Sinoussi,J.C. Chermann,J. B. Brunet,David Klatzmann,Jean Claude Gluckman +11 more
TL;DR: A strain of lymphadenopathy associated retrovirus passaged in vitro was used to infect a lymphoblastoid cell line obtained by transformation with Epstein-Barr virus of B lymphocytes from a healthy donor, and this adapted strain retained the biochemical, ultrastructural, and antigenic characteristics of the original strain.
Journal ArticleDOI
Cis elements and trans-acting factors involved in the RNA dimerization of the human immunodeficiency virus HIV-1.
Jean-Luc Darlix,Caroline Gabus,Marie-Thérèse Nugeyre,François Clavel,Françoise Barré-Sinoussi +4 more
TL;DR: It is reported that HIV-1 RNA forms dimeric molecules and that viral nucleocapsid protein NCp15 greatly activates dimerization, and cross-linking analysis of the interactions between NC and HIV- 1 RNA shows that NC protein molecules are tightly bound to the genomic RNA dimer.
Journal ArticleDOI
LAV revisited: origins of the early HIV-1 isolates from Institut Pasteur
Simon Wain-Hobson,Jean-Pierre Vartanian,Michel Henry,Nicole Chenciner,Rémi Cheynier,Sylvie Delassus,Livia Pedroza Martins,Monica Sala,Marie-Thérèse Nugeyre,Denise Guetard +9 more
TL;DR: Two of the first human immunodeficiency virus type-1 (HIV-1) strains isolated were authenticated by reanalyzing original cultured samples stored at the Collection Nationale de Culture des Microorganismes as well as uncultured primary material.