Marija Rankovic

TL;DR: It is reported that human and yeast CTDs undergo cooperative liquid phase separation, with the shorter yeast CTD forming less-stable droplets and that CTD phosphorylation liberates Pol II enzymes from hubs for promoter escape and transcription elongation.

TL;DR: It is shown that RNA induces cooperative liquid–liquid phase separation of the SARS-CoV-2 nucleocapsid protein, which generates high-density protein/RNA condensates that recruit the RNA-dependent RNA polymerase complex of SARS, providing a mechanism for efficient transcription of viral RNA.

TL;DR: In this article, the interaction of α-synuclein with tau and its consequences on tau LLPS was investigated, and it was shown that α-Synuclein has a low propensity for self-coacervation and RNA-mediated LLPS at pH 7.4.

TL;DR: It is suggested that Tau might play a previously underestimated role in neurodevelopmental disorders and regression in children, as well as several neurological conditions and diseases in an early life stage with upregulated levels or even pathological aggregation of abnormally phosphorylated Tau protein.

TL;DR: It is shown that RNA induces cooperative liquid-liquid phase separation of the SARS-CoV-2 nucleocapsid protein, which generates high-density protein/RNA condensates that recruit the RNA-dependent RNA polymerase complex of SARS, providing a mechanism for efficient transcription of viral RNA.