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Marilyn N. Martinez

Researcher at Food and Drug Administration

Publications -  98
Citations -  2862

Marilyn N. Martinez is an academic researcher from Food and Drug Administration. The author has contributed to research in topics: Veterinary drug & Population. The author has an hindex of 26, co-authored 98 publications receiving 2534 citations. Previous affiliations of Marilyn N. Martinez include Center for Veterinary Medicine.

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A Mechanistic Approach to Understanding the Factors Affecting Drug Absorption: A Review of Fundamentals

TL;DR: This article provides an overview of the patient‐specific and drug‐specific variables that can affect drug absorption following oral product administration and develops formulations that will maximize product availability.
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Pharmacology of the fluoroquinolones: a perspective for the use in domestic animals

TL;DR: This review focuses on the use of fluoroquinolones within veterinary medicine, providing an overview of the structure-activity relationship of the various members of the group, the clinical uses offluoroquolones in veterinary Medicine, their pharmacokinetics and potential interspecies differences, and a summary of toxicities associated with this class of compounds.
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Dosing Regimen Matters: the Importance of Early Intervention and Rapid Attainment of the Pharmacokinetic/Pharmacodynamic Target

TL;DR: This minireview provides an overview of published evidence supporting the positions that, in most situations, it is the exposure achieved during the first dose that is relevant for determining the therapeutic outcome of an infection and therapeutic intervention should be initiated as soon as possible to minimize the size of the bacterial burden at the infection site.
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Applying the biopharmaceutics classification system to veterinary pharmaceutical products. Part I: biopharmaceutics and formulation considerations.

TL;DR: This paper examines manufacturing and formulation variables that can affect drug bioavailability, and the potential for species-specific differences in the responses to these formulations.