M
Marilyne Labasque
Researcher at Centre national de la recherche scientifique
Publications - 3
Citations - 750
Marilyne Labasque is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Receptor & Phosphorylation. The author has an hindex of 3, co-authored 3 publications receiving 649 citations.
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Journal ArticleDOI
Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists
Thomas Papouin,Laurent Ladépêche,Laurent Ladépêche,Jérôme Ruel,Jérôme Ruel,Silvia Sacchi,Marilyne Labasque,Marwa Hanini,Laurent Groc,Laurent Groc,Loredano Pollegioni,Jean-Pierre Mothet,Stéphane H. R. Oliet,Stéphane H. R. Oliet +13 more
TL;DR: It is demonstrated that long-term potentiation and NMDA-induced neurotoxicity rely on synaptic NMDARs only, and long- term depression requires both synaptic and extrasynaptic receptors.
Journal ArticleDOI
Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling.
TL;DR: It is shown that calmodulin (CaM) binds to a prototypic Ca(2+)-dependent "1-10" CaM-binding motif located in the proximal region of the 5-HT(2C) receptor C-terminus upon receptor activation by5-HT, demonstrating that physical interaction of CaM with recombinant and native 5- HT(2 C) receptors is critical for G protein-independent, arrestin-dependent receptor signaling.
Journal ArticleDOI
Constitutive Activity of Serotonin2C Receptors at G Protein-Independent Signaling: Modulation by RNA Editing and Antidepressants
TL;DR: Basal ERK1/2 phosphorylation in 5-HT2C-INI receptor-expressing cells was abolished and evidence of constitutive activity of a G protein-coupled receptor toward G-independent, β-arrestin-dependent, receptor signaling is provided.