M
Marina Campos Rocha
Researcher at Federal University of São Carlos
Publications - 42
Citations - 740
Marina Campos Rocha is an academic researcher from Federal University of São Carlos. The author has contributed to research in topics: Aspergillus fumigatus & Transcription factor. The author has an hindex of 13, co-authored 38 publications receiving 479 citations.
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Journal ArticleDOI
Aspergillus fumigatus MADS-Box Transcription Factor rlmA Is Required for Regulation of the Cell Wall Integrity and Virulence
Marina Campos Rocha,João Henrique Tadini Marilhano Fabri,Krissia Franco de Godoy,Patrícia Alves de Castro,Juliana I. Hori,Anderson F. Cunha,Mark Arentshorst,Arthur F. J. Ram,Cees A. M. J. J. van den Hondel,Gustavo H. Goldman,Iran Malavazi +10 more
TL;DR: The results suggest that RlmA functions as a transcription factor in the A. fumigatus CWI pathway, acting downstream of PkcA-MpkA signaling and contributing to the virulence of this fungus.
Journal ArticleDOI
Mitogen activated protein kinases SakA(HOG1) and MpkC collaborate for Aspergillus fumigatus virulence
Ariane Cristina Mendes de Oliveira Bruder Nascimento,Thaila Fernanda dos Reis,Patrícia Alves de Castro,Juliana I. Hori,Vinícius Leite Pedro Bom,Leandro José de Assis,Leandra Naira Zambelli Ramalho,Marina Campos Rocha,Iran Malavazi,Neil Andrew Brown,Vito Valiante,Axel A. Brakhage,Daisuke Hagiwara,Gustavo H. Goldman +13 more
TL;DR: It is proposed that both cell wall integrity (CWI) and HOG pathways collaborate, and that MpkC could act by modulating SakA activity upon exposure to several types of stresses and during CW biosynthesis.
Journal ArticleDOI
The Aspergillus fumigatus CrzA Transcription Factor Activates Chitin Synthase Gene Expression during the Caspofungin Paradoxical Effect
Laure Nicolas Annick Ries,Marina Campos Rocha,Patrícia Alves de Castro,Rafael Silva-Rocha,Roberto Nascimento Silva,Fernanda Zanolli Freitas,Leandro José de Assis,Maria Célia Bertolini,Iran Malavazi,Gustavo H. Goldman +9 more
TL;DR: The CPE is dependent on the cell wall integrity (CWI) mitogen-activated protein kinase MpkAMPK1 and its associated transcription factor (TF) RlmARLM1, which regulate chitin synthase gene expression in response to different concentrations of caspofungin, and shows that the regulation of cell wall biosynthetic genes occurs by several cellular signaling pathways.
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Extracellular vesicles carry cellulases in the industrial fungus Trichoderma reesei .
Renato Graciano de Paula,Amanda Cristina Campos Antoniêto,Karoline Maria Vieira Nogueira,Liliane Fraga Costa Ribeiro,Marina Campos Rocha,Iran Malavazi,Fausto Almeida,Roberto Nascimento Silva +7 more
TL;DR: This work reports for the first time the isolation and characterization of T. reesei extracellular vesicles and points to important insights into a better understanding of the cellular mechanisms underlying the regulation of cellulolytic enzyme secretion in this fungus.
Journal ArticleDOI
The Aspergillus fumigatus pkcAG579R Mutant Is Defective in the Activation of the Cell Wall Integrity Pathway but Is Dispensable for Virulence in a Neutropenic Mouse Infection Model
Marina Campos Rocha,Krissia Franco de Godoy,Patrícia Alves de Castro,Juliana I. Hori,Vinícius Leite Pedro Bom,Neil Andrew Brown,Anderson F. Cunha,Gustavo H. Goldman,Gustavo H. Goldman,Iran Malavazi +9 more
TL;DR: The results suggest that pkcA is an essential gene and is activated in response to cell wall stress and indicated that additional regulatory circuits may be involved in the biosynthesis and/or reinforcement of the A. fumigatus cell wall during infection.