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Marina S. Ferguson

Researcher at University of Washington

Publications -  79
Citations -  12428

Marina S. Ferguson is an academic researcher from University of Washington. The author has contributed to research in topics: Carotid endarterectomy & Magnetic resonance imaging. The author has an hindex of 45, co-authored 78 publications receiving 11841 citations. Previous affiliations of Marina S. Ferguson include University of Tampere.

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Classification of human carotid atherosclerotic lesions with in vivo multicontrast magnetic resonance imaging.

TL;DR: In vivo high-resolution multicontrast MRI is capable of classifying intermediate to advanced atherosclerotic lesions in the human carotid artery and is also capable of distinguishing advanced lesions from early and intermediate atherosclerosis plaque.
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In vivo accuracy of multispectral magnetic resonance imaging for identifying lipid-rich necrotic cores and intraplaque hemorrhage in advanced human carotid plaques.

TL;DR: This study evaluated differential contrast-weighted images, specifically a multispectral MR technique, to improve the accuracy of identifying the lipid-rich necrotic core and acute intraplaque hemorrhage in vivo.
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Association Between Carotid Plaque Characteristics and Subsequent Ischemic Cerebrovascular Events A Prospective Assessment With MRI—Initial Results

TL;DR: Among patients who initially had an asymptomatic 50% to 79% carotid stenosis, arteries with thinned or ruptured fibrous caps, intraplaque hemorrhage, larger maximum %lipid-rich/necrotic cores, and larger maximum wall thickness by MRI were associated with the occurrence of subsequent cerebrovascular events.
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Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques. Implications for the mode of progression of advanced coronary atherosclerosis.

TL;DR: The results document the presence of VCAM-1 in human atherosclerosis, demonstrate VCAM1 expression by human smooth muscle cells in vivo, and suggest that intimal neovasculature may be an important site of inflammatory cell recruitment into advanced coronary lesions.
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Quantitative Evaluation of Carotid Plaque Composition by In Vivo MRI

TL;DR: MRI-based tissue quantification is accurate and reproducible and can be used in therapeutic clinical trials and in prospective longitudinal studies to examine carotid atherosclerotic plaque progression and regression.