M
Marion Cornelissen
Researcher at University of Amsterdam
Publications - 106
Citations - 4577
Marion Cornelissen is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Virus & Viral load. The author has an hindex of 36, co-authored 104 publications receiving 4260 citations.
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Journal ArticleDOI
Detection and Typing of Human Papillomavirus in Archival Cervical Cancer Specimens by DNA Amplification With Consensus Primers
Robert M. Resnick,Marion Cornelissen,Deann K. Wright,Greg H. Eichinger,Howard S. Fox,Jan ter Schegget,M. Michele Manos +6 more
TL;DR: A polymerase chain reaction DNA amplification system using two distinct consensus oligonucleotide primer sets for the improved detection and typing of a broad spectrum of human genital papillomavirus (HPV) sequences, including those of novel viruses.
Journal ArticleDOI
Association between CCR5 Genotype and the Clinical Course of HIV-1 Infection
A.M. de Roda Husman,M. Koot,Marion Cornelissen,I. P. M. Keet,M. Brouwer,S. Broersen,Marleen Bakker,Marijke T. L. Roos,Maria Prins,F. De Wolf,R. A. Coutinho,Frank Miedema,Jaap Goudsmit,Hanneke Schuitemaker +13 more
TL;DR: The role of CCR5 genotype alone and in relation to established progression markers in the clinical course of HIV-1 infection in participants from the Amsterdam Cohort Studies suggested a good estimation of the seroconversion date in the latter group.
Journal ArticleDOI
Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping
Paula J P de Vree,Elzo de Wit,Mehmet Yilmaz,Monique van de Heijning,Petra Klous,Marjon J.A.M. Verstegen,Yi Wan,Hans Teunissen,Peter H.L. Krijger,Geert Geeven,Paul P. Eijk,Daoud Sie,Bauke Ylstra,Lorette O M Hulsman,Marieke F. van Dooren,Laura J. C. M. van Zutven,Ans M.W. van den Ouweland,Sjef Verbeek,Ko Willems van Dijk,Marion Cornelissen,Atze T. Das,Ben Berkhout,Birgit Sikkema-Raddatz,Eva van den Berg,Pieter van der Vlies,Desiree Weening,Johan T. den Dunnen,Magdalena Matusiak,Mohamed Lamkanfi,Marjolijn J. L. Ligtenberg,Petra ter Brugge,Jos Jonkers,John A. Foekens,John W. M. Martens,Rob B. van der Luijt,Hans Kristian Ploos van Amstel,Max van Min,Erik Splinter,Wouter de Laat +38 more
TL;DR: Target locus amplification (TLA) is presented, a strategy to selectively amplify and sequence entire genes on the basis of the crosslinking of physically proximal sequences that enables robust detection of single nucleotide variants, structural variants and gene fusions in clinically relevant genes, and enables haplotyping.
Journal ArticleDOI
Syncytium-inducing (SI) phenotype suppression at seroconversion after intramuscular inoculation of a non-syncytium-inducing/SI phenotypically mixed human immunodeficiency virus population.
Marion Cornelissen,Mulder-Kampinga Ga,J Veenstra,Fokla Zorgdrager,C L Kuiken,Susan Hartman,J. Dekker,L. van der Hoek,C. J. A. Sol,Roel A. Coutinho +9 more
TL;DR: Study of two cases of accidental transmission suggests that the suppression of SI viruses can be accomplished following the development of HIV-specific immunity and that the ability to suppress SI viruses does not prevent theDevelopment of immunodeficiency.
Journal ArticleDOI
pol gene diversity of five human immunodeficiency virus type 1 subtypes: evidence for naturally occurring mutations that contribute to drug resistance, limited recombination patterns, and common ancestry for subtypes B and D.
TL;DR: It is shown that gag and pol are subjected to purifying selection with an average ds/da ratio above 1, independent of the subtype and in contrast with V3, and a common ancestry for subtypes B and D that is distinct from that of subtypes A and E.