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Marion Cornelissen

Researcher at University of Amsterdam

Publications -  106
Citations -  4577

Marion Cornelissen is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Virus & Viral load. The author has an hindex of 36, co-authored 104 publications receiving 4260 citations.

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Detection and Typing of Human Papillomavirus in Archival Cervical Cancer Specimens by DNA Amplification With Consensus Primers

TL;DR: A polymerase chain reaction DNA amplification system using two distinct consensus oligonucleotide primer sets for the improved detection and typing of a broad spectrum of human genital papillomavirus (HPV) sequences, including those of novel viruses.
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Association between CCR5 Genotype and the Clinical Course of HIV-1 Infection

TL;DR: The role of CCR5 genotype alone and in relation to established progression markers in the clinical course of HIV-1 infection in participants from the Amsterdam Cohort Studies suggested a good estimation of the seroconversion date in the latter group.
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Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping

TL;DR: Target locus amplification (TLA) is presented, a strategy to selectively amplify and sequence entire genes on the basis of the crosslinking of physically proximal sequences that enables robust detection of single nucleotide variants, structural variants and gene fusions in clinically relevant genes, and enables haplotyping.
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Syncytium-inducing (SI) phenotype suppression at seroconversion after intramuscular inoculation of a non-syncytium-inducing/SI phenotypically mixed human immunodeficiency virus population.

TL;DR: Study of two cases of accidental transmission suggests that the suppression of SI viruses can be accomplished following the development of HIV-specific immunity and that the ability to suppress SI viruses does not prevent theDevelopment of immunodeficiency.
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pol gene diversity of five human immunodeficiency virus type 1 subtypes: evidence for naturally occurring mutations that contribute to drug resistance, limited recombination patterns, and common ancestry for subtypes B and D.

TL;DR: It is shown that gag and pol are subjected to purifying selection with an average ds/da ratio above 1, independent of the subtype and in contrast with V3, and a common ancestry for subtypes B and D that is distinct from that of subtypes A and E.