M
Marjorie Monleau
Researcher at Institut de recherche pour le développement
Publications - 11
Citations - 469
Marjorie Monleau is an academic researcher from Institut de recherche pour le développement. The author has contributed to research in topics: Drug resistance & Viral load. The author has an hindex of 8, co-authored 11 publications receiving 437 citations. Previous affiliations of Marjorie Monleau include University of Montpellier.
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Journal ArticleDOI
Evaluation of Different RNA Extraction Methods and Storage Conditions of Dried Plasma or Blood Spots for Human Immunodeficiency Virus Type 1 RNA Quantification and PCR Amplification for Drug Resistance Testing
Marjorie Monleau,Celine Montavon,Christian Laurent,Michel Segondy,Brigitte Montes,Eric Delaporte,François Boillot,Martine Peeters +7 more
TL;DR: The RNA extraction method is an important factor in obtaining reliable RNA quantification and PCR amplification of HIV-1 on DPS/DBS and can be used as an alternative for DPS depending on HIV RNA cutoffs for virological failure.
Journal ArticleDOI
Extraordinary Heterogeneity of Virological Outcomes in Patients Receiving Highly Antiretroviral Therapy and Monitored With the World Health Organization Public Health Approach in Sub-Saharan Africa and Southeast Asia
Avelin F. Aghokeng,Marjorie Monleau,Sabrina Eymard-Duvernay,Anoumou Dagnra,Dramane Kania,Nicole Ngo-Giang-Huong,Thomas d. 'Aquin Toni,Coumba Toure-Kane,Lien X. T. Truong,Eric Delaporte,Marie-Laure Chaix,Martine Peeters,Ahidjo Ayouba +12 more
TL;DR: The findings show heterogeneous virological failure and illustrate that, in addition to routine access to viral load, good management of ART programs is even more critical to improve treatment outcomes in resource-limited countries.
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Effect of storage conditions of dried plasma and blood spots on HIV-1 RNA quantification and PCR amplification for drug resistance genotyping
TL;DR: Virological monitoring is still feasible for DBS after 3 months of storage at 37 degrees C when VL is >5000 copies/mL, but DNA contributes largely to the final results.
Journal ArticleDOI
Field Evaluation of Dried Blood Spots for Routine HIV-1 Viral Load and Drug Resistance Monitoring in Patients Receiving Antiretroviral Therapy in Africa and Asia
Marjorie Monleau,Avelin F. Aghokeng,Sabrina Eymard-Duvernay,Anoumou Y. Dagnra,Dramane Kania,Nicole Ngo-Giang-Huong,Coumba Toure-Kane,Lien X. T. Truong,Marie-Laure Chaix,Eric Delaporte,Ahidjo Ayouba,Martine Peeters +11 more
TL;DR: DBS can be successfully used as an alternative to blood plasma samples for routine VL and HIVDR monitoring in African and Asian settings, however, the selection of an adequate VL measurement method and the definition of the VF threshold should be considered, and laboratory performance should be monitored.
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High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lomé, Togo
Anoumou Y. Dagnra,Nicole Vidal,Akovi Mensah,Akouda Patassi,Komi Aho,Mounerou Salou,Marjorie Monleau,Mireille Prince-David,Assétina Singo,Palokinam Pitché,Eric Delaporte,Martine Peeters +11 more
TL;DR: The high number of resistant strains observed in Togo shows clearly that the emergence of HIV drug resistance is of increasing concern in countries where ART is now widely used, and can compromise the long-term success of first- and second-line ART.