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Mark A. van Buchem

Researcher at Leiden University

Publications -  69
Citations -  9696

Mark A. van Buchem is an academic researcher from Leiden University. The author has contributed to research in topics: Hyperintensity & Population. The author has an hindex of 37, co-authored 69 publications receiving 7671 citations. Previous affiliations of Mark A. van Buchem include Leiden University Medical Center.

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Frontal lobe structure and executive function in migraine patients

TL;DR: Migraineurs showed decreased frontal and parietal lobe GM density and slower response time to task set-shifting and, the delayed response time correlated significantly with reduced GM density of the frontal lobes in migraineurs.
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Endogenous cortisol is associated with functional connectivity between the amygdala and medial prefrontal cortex

TL;DR: The results corroborate previous findings from both animal and human studies, suggesting cortisol-mediated regulation of the amygdala by the mPFC and propose that through this feedback mechanism the stress response might be adjusted, pointing to the putative role of cortisol in modulating stress- and, more generally, emotional responses.
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Cortical Iron Reflects Severity of Alzheimer's Disease.

TL;DR: In this article, the authors used formalin fixed paraffin embedded frontal cortex from 10 AD patients, 10 elder, 10 middle aged, and 10 young controls and visualized iron with a modified Perl's histochemical procedure.
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Practice effects in the brain: Changes in cerebral activation after working memory practice depend on task demands.

TL;DR: It is demonstrated that practice was beneficial for both working memory maintenance and manipulation processes but that these processes were supported by different neural changes, which illustrate the importance of controlling for test-retest effects in training or intervention studies.