M
Mark E. Wong
Researcher at University of Texas Health Science Center at Houston
Publications - 79
Citations - 4630
Mark E. Wong is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Bone regeneration & PLGA. The author has an hindex of 29, co-authored 75 publications receiving 4121 citations. Previous affiliations of Mark E. Wong include University of Texas at Austin & University of Texas Health Science Center at San Antonio.
Papers
More filters
Journal ArticleDOI
Automated Selection of DAB-labeled Tissue for Immunohistochemical Quantification
Eric M. Brey,Zahid Lalani,Carol Johnston,Mark E. Wong,Larry V. McIntire,Pauline Jackie Duke,Charles W. Patrick +6 more
TL;DR: A novel imaging technique in which brightfield images of diaminobenzidene (DAB)-labeled antigens are converted to normalized blue images, allowing automated identification of positively stained tissue and was statistically the most accurate and consistent across all staining levels.
Journal ArticleDOI
Dual growth factor delivery from bilayered, biodegradable hydrogel composites for spatially-guided osteochondral tissue repair
Steven Lu,Johnny Lam,Jordan E. Trachtenberg,Esther J. Lee,Hajar Seyednejad,Jeroen J.J.P. van den Beucken,Yasuhiko Tabata,Mark E. Wong,John A. Jansen,Antonios G. Mikos,F. Kurtis Kasper +10 more
TL;DR: Overall, bilayered OPF hydrogel composites demonstrate potential as spatially-guided, multiple growth factor release vehicles for osteochondral tissue repair and that, while the dual delivery of IGF-1 and BMP-2 in separate layers does not improve cartilage repair under the conditions studied, they may synergistically enhance the degree of subchondral bone formation.
Journal ArticleDOI
Osteochondral Tissue Regeneration using a Bilayered Composite Hydrogel with Modulating Dual Growth Factor Release Kinetics in a Rabbit Model
Kyobum Kim,Johnny Lam,Steven Lu,Patrick P. Spicer,Aline Lueckgen,Yasuhiko Tabata,Mark E. Wong,John A. Jansen,Antonios G. Mikos,F. Kurtis Kasper +9 more
TL;DR: The results suggest that although the dual delivery of TGF-β3 and IGF-1 may not synergistically enhance the quality of engineered tissue, the delivery of IGF- 1 alone from bilayered composite hydrogels positively affects osteochondral tissue repair and holds promise for oste mitochondral tissue engineering applications.
Journal ArticleDOI
The integrated processes of hard tissue regeneration with special emphasis on fracture healing
TL;DR: Some of the exciting biologic regulators relevant to bone fracture healing are highlighted and the dynamic elements in this process are outlined.
Journal ArticleDOI
An Interspecies Comparison of the Temporomandibular Joint Disc
TL;DR: While human discs possessed properties distinct from those of the other species, pig discs were most similar to the human, suggesting that the pig may be a suitable animal model for TMJ bioengineering efforts.