M
Mark J. Kupersmith
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 155
Citations - 6723
Mark J. Kupersmith is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Optic neuritis & Papilledema. The author has an hindex of 40, co-authored 146 publications receiving 6028 citations. Previous affiliations of Mark J. Kupersmith include Mount Sinai St. Luke's and Mount Sinai Roosevelt & New York Eye and Ear Infirmary.
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Journal ArticleDOI
A Randomized, Controlled Trial of Corticosteroids in the Treatment of Acute Optic Neuritis
Roy W. Beck,Patricia A. Cleary,Malcolm M. Anderson,John L. Keltner,William T. Shults,David I. Kaufman,Edward G. Buckley,James J. Corbett,Mark J. Kupersmith,Neil R. Miller,Peter J. Savino,John Guy,Jonathan D. Trobe,John A. McCrary,Craig H. Smith,Georgia A. Chrousos,H. Stanley Thompson,Barrett Katz,Michael C. Brodsky,James Goodwin,Constance W. Atwell +20 more
TL;DR: Although the differences between the groups decreased with time, at six months the group that received intravenous methylprednisolone still had slightly better visual fields, contrast sensitivity, and color vision but not better visual acuity.
Journal ArticleDOI
Multiple sclerosis risk after optic neuritis: Final optic neuritis treatment trial follow-up
Michael C. Brodsky,Michael C. Brodsky,Sarkis Nazarian,Silvia Orengo-Nania,George J. Hutton,Edward G. Buckley,E. Wayne Massey,M. Tariq Bhatti,M. Tariq Bhatti,Melvin Greer,James Goodwin,Michael Wall,Peter J. Savino,Thomas Leist,Neil R. Miller,David N. Irani,Jonathan D. Trobe,Wayne T. Cornblath,David I. Kaufman,Eric R. Eggenberger,Mark J. Kupersmith,William T. Shults,Leslie McAllister,Steve Hamilton,Roy W. Beck,Mariya Dontchev,Robin L. Gal,Craig Kollman,John L. Keltner,Craig H. Smith +29 more
TL;DR: The presence of brain MRI abnormalities at the time of an optic neuritis attack is a strong predictor of the 15-year risk of MS.
Journal ArticleDOI
High- and low-risk profiles for the development of multiple sclerosis within 10 years after optic neuritis: experience of the optic neuritis treatment trial.
Roy W. Beck,Jonathan D. Trobe,Pamela S. Moke,Robin L. Gal,Xing D,Bhatti Mt,Michael C. Brodsky,Edward G. Buckley,Georgia A. Chrousos,James J. Corbett,Eric R. Eggenberger,James Goodwin,Barrett Katz,David I. Kaufman,John L. Keltner,Mark J. Kupersmith,Neil R. Miller,Sarkis M. Nazarian,Silvia Orengo-Nania,Peter J. Savino,William T. Shults,Craig H. Smith,Michael Wall +22 more
TL;DR: Natural history information is a critical input for estimating a patient's 10-year multiple sclerosis risk and for weighing the benefit of initiating prophylactic treatment at the time of optic neuritis or other initial demyelinating events in the central nervous system.
Journal ArticleDOI
Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: the idiopathic intracranial hypertension treatment trial.
Michael Wall,Michael P. McDermott,Karl Kieburtz,James J. Corbett,Steven E. Feldon,Deborah I. Friedman,David M. Katz,John L. Keltner,Eleanor Schron,Mark J. Kupersmith +9 more
TL;DR: Whether acetazolamide is beneficial in improving vision when added to a low-sodium weight reduction diet in patients with IIH and mild visual loss is investigated to establish an evidence base for its use.
Journal ArticleDOI
The idiopathic intracranial hypertension treatment trial clinical profile at baseline
Michael Wall,Mark J. Kupersmith,Karl Kieburtz,James J. Corbett,Steven E. Feldon,Deborah I. Friedman,David M. Katz,John L. Keltner,Eleanor Schron,Michael P. McDermott +9 more
TL;DR: The data show that IIH is almost exclusively a disease of obese young women and quality of life measures, including the National Eye Institute Visual Function Questionnaire-25 and the Short Form-36 physical and mental health summary scales, were lower compared with population norms.