Mark Kuehnel

TL;DR: It is suggested that venous occlusions in PVOD increase shear and stretching forces in the pulmonary capillary bloodstream and thereby induce intussusceptive neoangiogenesis, which can serve as a basis for novel approaches to the analysis of PVOD.

TL;DR: Findings indicate that PTSMT’s growth is driven by two factors of the wingless-type protein family: WNT6 and WNT10A, and a non-canonical activation of WNT, independent of beta-catenin, drives tumor cell proliferation via MTOR/AKT1, MYC and Cyclin D2.

TL;DR: Comparison of morphological and transcriptional data indicate that the neovascularization by intussusceptive angiogenesis is the main driver for a specific COVID-19 induced cardiac response facilitated by interactions between the incorporation of blood-borne CD11b+/Tie2+ monocytes/ macrophages and damaged and activated endothelial cells in CO VID-19 hearts.

TL;DR: A method to characterize the topology of the mouse airway tree using scanning laser optical tomography (SLOT) tomograms is presented and is used to test discrimination between two types of mice based on detected differences in their conducting airway pattern.

TL;DR: In this article , the authors demonstrate that ER-mitochondrial tethering is reduced upon experimental ER stress in vitro and in the IPF AECII ex vivo, and this is-at least in part-due to decreased phosphofurin acidic cluster sorting protein 2 (PACS-2), also called PACS2) protein levels.