Mark L. Pearson

TL;DR: The complete nucleotide sequence of two human T-cell leukaemia type III (HTLV-III) proviral DNAs each have four long open reading frames, the first two corresponding to the gag and pol genes.

TL;DR: Newly determined sequences are reported for 3'orf of two unintegrated clones of HTLV-III and three cDNA clones made from virion RNA derived from the same cell line infected with pooled blood samples of different patients with AIDS or AIDS-related complex symptoms (ARC).

TL;DR: Preliminary secondary structural predictions suggest that the C-terminal half of the protein is likely an α/β-type protein and placement in the sequence of two peptides found in previous cross-linking studies reveals two stretches of primary structure that are presumably close in space to the reactive Cys-283 and hence close to the active site.

TL;DR: Examination of ckb RNA from brain tissue provides no evidence for the existence of more than one set of transcriptional start points, and the ckm and ckb genes show little homology in the 5'-flanking regions, although some sequence conservation in the regions immediately surrounding the CAAT and TATA sequences.

TL;DR: The coding sequence of this clone has enabled us to deduce the complete amino acid (aa) sequence of rat CKB protein.