M
Mark M. Rich
Researcher at Wright State University
Publications - 62
Citations - 4147
Mark M. Rich is an academic researcher from Wright State University. The author has contributed to research in topics: Motor neuron & Neuromuscular junction. The author has an hindex of 30, co-authored 54 publications receiving 3757 citations. Previous affiliations of Mark M. Rich include Emory University & The Ohio State University Wexner Medical Center.
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Journal ArticleDOI
Impaired Synaptic Vesicle Release and Immaturity of Neuromuscular Junctions in Spinal Muscular Atrophy Mice
Lingling Kong,Xueyong Wang,Dong W. Choe,Michelle Polley,Barrington G. Burnett,Marta Bosch-Marce,John W. Griffin,Mark M. Rich,Charlotte J. Sumner +8 more
TL;DR: Results indicate that impaired synaptic vesicle release at NMJs in severe SMA is likely to contribute to failed postnatal maturation of motor units and muscle weakness.
Journal ArticleDOI
Mice lacking the myotonic dystrophy protein kinase develop a late onset progressive myopathy.
Sita Reddy,Daniel J. Smith,Mark M. Rich,John Leferovich,Patricia Anne Reilly,Brigid M. Davis,Khoa D. Tran,Helen Rayburn,Roderick T. Bronson,Didier Cros,Rita J. Balice-Gordon,David E. Housman +11 more
TL;DR: The results indicate that D MPK may be necessary for the maintenance of skeletal muscle structure and function and suggest that a decrease in DMPK levels may contribute to DM pathology.
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An Official American Thoracic Society Clinical Practice Guideline: The Diagnosis of Intensive Care Unit–acquired Weakness in Adults
Eddy Fan,Fern Cheek,Linda L. Chlan,Rik Gosselink,Nicholas Hart,Margaret S. Herridge,Ramona O. Hopkins,Catherine L. Hough,John P. Kress,Nicola Latronico,Marc Moss,Dale M. Needham,Mark M. Rich,Robert Stevens,Kevin C. Wilson,Chris Winkelman,Doug W. Zochodne,Naeem A. Ali +17 more
TL;DR: Research that identifies treatments that benefit patients with ICUAW is necessary to determine whether the benefits of diagnostic testing forICUAW outweigh its burdens.
Journal ArticleDOI
Direct muscle stimulation in acute quadriplegic myopathy
TL;DR: Direct muscle stimulation may allow differentiation of AQM from neuropathy even in comatose or encephalopathic critically ill patients, and may be more common than has previously been appreciated.
Journal ArticleDOI
The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill
Oliver Friedrich,Michael B. Reid,G Van den Berghe,Ilse Vanhorebeek,Greet Hermans,Mark M. Rich,Lars Larsson +6 more
TL;DR: A classification of different ICUAW forms (CIM, CIP, sepsis-induced, steroid-denervation myopathy) and pathophysiological mechanisms from clinical and animal model data are proposed and highlighted, allowing separation of risk factors that may trigger distinct mechanisms contributing to weakness.