Mark McLaughlin

TL;DR: A novel role for oligodendrocytes in the local regulation of axonal function is demonstrated and implications for the axonal loss associated with secondary progressive multiple sclerosis are implications.

TL;DR: Overall, the COST Action on Farm Animal Proteomics has attained all of the proposed objectives and has made considerable difference by putting proteomics on the global map for animal and veterinary researchers in general and by contributing significantly to reduce the East–West and North–South gaps existing in the European farm animal research.

TL;DR: Observe that mice deficient in both CNP and PLP develop a more severe axonal phenotype than either single mutant, indicating that the two oligodendroglial proteins serve distinct functions in supporting the myelinated axon, and support a model in which the trophic functions of oligodendedrocytes serve to offset the physical shielding of axons by myelin membranes.

TL;DR: The prednisolone regimen presented was successful in treating steroid responsive meningitis-arteritis without the need for additional drugs and serum APPs are of use in the diagnosis and management of SRMA, particularly in relation to identifying relapse.

TL;DR: There was no significant difference in the level of Gα subunits of five G proteins between Alzheimer's diseased and age‐matched postmortem brains, suggesting that alterations in the amount of G protein α subunits are not a feature of Alzheimer's disease.