Mark Palazzo

TL;DR: The use of dobutamine to boost the cardiac index and systemic oxygen delivery failed to improve the outcome in this heterogeneous group of critically ill patients, and it is suggested that in some cases aggressive efforts to increase oxygen consumption may have been detrimental.

TL;DR: The crude incidence of ICU infections remains high, although the rate varies between ICUs and patient subsets, illustrating the added burden of nosocomial infections in the use ofICU resources.

TL;DR: In this article, a randomized trial was conducted to determine whether boosting oxygen delivery by infusing the inotropic agent dobutamine would improve the outcome in a diverse group of critically ill patients.

TL;DR: A score estimating this risk, using objectively defined criteria for systemic inflammatory response syndrome, could be used by physicians to stratify patients for clinical management and to test new interventions.

TL;DR: Survivors of sepsis syndrome or septic shock are characterized by an ability to increase both DO2 andVO2, which may help to explain the findings by some investigators that treatment aimed at achieving survivor values of cardiac index, DO2, and VO2 fails to improve outcome when instituted following admission to intensive care.