M
Mark R. McCoy
Researcher at University of California, Davis
Publications - 20
Citations - 664
Mark R. McCoy is an academic researcher from University of California, Davis. The author has contributed to research in topics: Phagemid & Status epilepticus. The author has an hindex of 11, co-authored 18 publications receiving 604 citations. Previous affiliations of Mark R. McCoy include Alaska Department of Fish and Game & University of Alaska Anchorage.
Papers
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Journal ArticleDOI
Gas chromatographic quantification of fatty acid methyl esters: flame ionization detection vs. electron impact mass spectrometry.
TL;DR: The capacity to combine spectrometric examination and quantitative determination advances GC-MS as a powerful alternative to GC-FID for FAME analysis—an approach that would be particularly advantageous for Fame determination in complex biological samples, where spectromaetric confirmation of analytes is advisable.
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Isolation of Alpaca Anti-Hapten Heavy Chain Single Domain Antibodies for Development of Sensitive Immunoassay
Hee Joo Kim,Mark R. McCoy,Zuzana Majkova,Julie E. Dechant,Shirley J. Gee,Sofía Tabares-da Rosa,Gualberto González-Sapienza,Bruce D. Hammock +7 more
TL;DR: A highly specific and sensitive VHH for 3-PBA was developed using sequences from immunized alpaca and phage display technology for antibody selection.
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Microscale recovery of total lipids from fish tissue by accelerated solvent extraction
TL;DR: The adaptation of previously developed lipid extraction solvent systems for use with accelerated solvent extraction technology demonstrates that microscale ASE represents an effective and efficient alternative to traditional lipid extraction techniques based on quantity and composition of extracted lipid, surrogate recovery, and precision.
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Tetramethylenedisulfotetramine Alters Ca2+ Dynamics in Cultured Hippocampal Neurons: Mitigation by NMDA Receptor Blockade and GABAA Receptor-Positive Modulation
Zhengyu Cao,Bruce D. Hammock,Mark R. McCoy,Michael A. Rogawski,Pamela J. Lein,Isaac N. Pessah +5 more
TL;DR: Low, minimally effective concentrations of diazepam and allopregnanolone were highly effective in suppressing TETS-induced alterations in Ca²⁺ dynamics, suggesting that the combination of positive modulators of synaptic and extrasynaptic GABA(A) receptors may have therapeutic potential.
Journal ArticleDOI
Engineered antibody fragments with infinite affinity as reporter genes for PET imaging.
Liu H. Wei,Tove Olafsen,Caius G. Radu,Isabel J. Hildebrandt,Mark R. McCoy,Michael E. Phelps,Claude F. Meares,Anna M. Wu,Johannes Czernin,Wolfgang A. Weber +9 more
TL;DR: Findings indicate that cell surface expression of radiometal chelate binding antibodies such as 2D12.5/G54C is a promising strategy for reporter gene imaging.