Mark Vasser

TL;DR: Two hybrid promoters that are functional in Escherichia coli have been constructed and are useful for the controlled expression of foreign genes at high levels in E. coli.

TL;DR: A method is described for the efficient insertion of mutagenic oligodeoxynucleotide cassettes which allow saturation of a target amino acid codon with multiple mutations.

TL;DR: This fully synthetic, minimalist library has essentially recapitulated the capacity of the natural immune system to generate high-affinity antibodies by systematically augmented the original binary library with additional levels of diversity and examined the effects.

TL;DR: It is concluded that efficient mRNA translation is required for maintaining mRNA stability in S. cerevisiae and these findings have important implications for the study of the expression of heterologous genes in yeast cells.

TL;DR: It is shown that the deubiquitylating enzyme DUBA is a negative regulator of IL-17A production in T cells, and that DUBA accumulated in activated T cells and stabilized UBR5, which then ubiquitylated RORγt in response to TGF-β signalling.