M
Mark W. Tibbitt
Researcher at ETH Zurich
Publications - 88
Citations - 8018
Mark W. Tibbitt is an academic researcher from ETH Zurich. The author has contributed to research in topics: Self-healing hydrogels & Medicine. The author has an hindex of 31, co-authored 74 publications receiving 6232 citations. Previous affiliations of Mark W. Tibbitt include Howard Hughes Medical Institute & University of Zurich.
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Hydrogels as Extracellular Matrix Mimics for 3D Cell Culture
TL;DR: The use of both synthetic and natural hydrogels as scaffolds for three-dimensional cell culture as well as synthetic hydrogel hybrids that incorporate sophisticated biochemical and mechanical cues as mimics of the native extracellular matrix are discussed.
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Mechanical memory and dosing influence stem cell fate.
TL;DR: It is concluded that stem cells possess mechanical memory - with YAP/TAZ acting as an intracellular mechanical rheostat - that stores information from past physical environments and influences the cells’ fate.
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Emerging Frontiers in Drug Delivery
TL;DR: There are highlights of four emerging areas in the field of drug delivery: systemic RNA delivery, drug delivery for localized therapy, oral drug delivery systems, and biologic drugDelivery systems, where the barriers to effective drug delivery as well as chemical and materials advances are presented.
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Self-assembled hydrogels utilizing polymer–nanoparticle interactions
TL;DR: This work develops a physical description of polymer-nanoparticle gel formation that is utilised to design biocompatible gels for minimally-invasive drug delivery and introduces a facile and generalizable class of mouldable hydrogels amenable to a range of biomedical and industrial applications.
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Synthesis of photodegradable hydrogels as dynamically tunable cell culture platforms
TL;DR: A detailed procedure to create photolabile, polyethylene glycol (PEG)-based hydrogels and manipulate material properties in situ to probing the dynamic influence of cell-cell and cell-material interactions on cell function in 2D or 3D.