Markus Heine

TL;DR: Zwitterion-coated exceedingly small superparamagnetic iron oxide nanoparticles (ZES-SPIONs) as discussed by the authors are free of Gd and show a high T1 contrast power.

TL;DR: Data indicate that NPs in vivo should no longer be considered as homogeneous entities, but should be seen as inorganic/organic/biological nano-hybrids with complex and intricately linked distribution and degradation pathways.

TL;DR: Differences between master and the peripheral clocks suggest that coupling‐induced rigidity in the SCN filters environmental noise to create a robust circadian system.

TL;DR: A large scale analysis of the CCG promoters reveals the complexity and extensiveness of the circadian regulation in mammals and points to connections of the calendar clock to other functional systems including metabolism, endocrine regulation and pharmacokinetics.

TL;DR: It is reported that cold exposure in mice triggers a metabolic program that orchestrates lipoprotein processing in brown adipose tissue (BAT) and hepatic conversion of cholesterol to bile acids via the alternative synthesis pathway, highlighting the relevance of cholesterol metabolism by the host for diet-induced changes of the gut microbiota and energy metabolism.