M
Markus M. Heiss
Researcher at Witten/Herdecke University
Publications - 135
Citations - 5888
Markus M. Heiss is an academic researcher from Witten/Herdecke University. The author has contributed to research in topics: Catumaxomab & Cancer. The author has an hindex of 37, co-authored 130 publications receiving 5580 citations. Previous affiliations of Markus M. Heiss include Ludwig Maximilian University of Munich.
Papers
More filters
Journal ArticleDOI
The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial
Markus M. Heiss,Pawel Murawa,Piotr Koralewski,Elzbieta Kutarska,Olena O. Kolesnik,Vladimir V. Ivanchenko,Alexander S. Dudnichenko,Birute Aleknaviciene,Arturas Razbadauskas,Martin Gore,Elena Ganea-Motan,Tudor Ciuleanu,Pauline Wimberger,Alexander Schmittel,Barbara Schmalfeldt,Alexander Burges,Carsten Bokemeyer,Horst Lindhofer,Angelika Lahr,Simon L. Parsons +19 more
TL;DR: Catumaxomab showed a clear clinical benefit in patients with malignant ascites secondary to epithelial cancers, especially gastric cancer, with an acceptable safety profile.
Journal Article
E-Cadherin Expression in Primary and Metastatic Gastric Cancer: Down-Regulation Correlates with Cellular Dedifferentiation and Glandular Disintegration
Barbara Mayer,Judith P. Johnson,Florian Leitl,Karl W. Jauch,Markus M. Heiss,Friedrich W. Schildberg,Walter Birchmeier,Ilona Funke +7 more
TL;DR: Evaluation of multiple metastases in 11 patients revealed uniformly strong E-cadherin expression in liver metastases, suggesting a possible regulatory role of the microenvironment.
Journal ArticleDOI
Beneficial effect of autologous blood transfusion on infectious complications after colorectal cancer surgery
Markus M. Heiss,K. W. Jauch,Christian Delanoff,G. Mayer,F-W. Schildberg,Wolfgang Mempel,M. Mempel,H-J. Eissner +7 more
TL;DR: The clinical potential of blood-transfusion-mediated immunomodulation, which may be important also in tumour immunology, is shown in patients with apparently curable colorectal cancer.
Journal ArticleDOI
Blood transfusion-modulated tumor recurrence: first results of a randomized study of autologous versus allogeneic blood transfusion in colorectal cancer surgery.
Markus M. Heiss,W. Mempel,C Delanoff,K. W. Jauch,C Gabka,M. Mempel,H J Dieterich,H J Eissner,Friedrich W. Schildberg +8 more
TL;DR: The blood transfusion modality has a significant effect on tumor recurrence after surgical treatment of colorectal cancer and might thus potentially surpass the impact of any recent adjuvant treatment strategies.
Journal ArticleDOI
c-erbB-2 is of independent prognostic relevance in gastric cancer and is associated with the expression of tumor-associated protease systems
Heike Allgayer,Rudolf Babic,Klaus Uwe Gruetzner,Anwar Tarabichi,Friedrich W. Schildberg,Markus M. Heiss +5 more
TL;DR: In this paper, a large-scale prospective series of 203 gastric cancer patients (median follow-up, 42 months) was used to evaluate the prognostic value of the c-erbB-2 gene in a large prospective series using a monoclonal antibody and immunohistochemical method.