M
Marleen H. van Coevorden-Hameete
Researcher at Utrecht University
Publications - 7
Citations - 170
Marleen H. van Coevorden-Hameete is an academic researcher from Utrecht University. The author has contributed to research in topics: Autoantibody & Paraneoplastic cerebellar degeneration. The author has an hindex of 7, co-authored 7 publications receiving 119 citations. Previous affiliations of Marleen H. van Coevorden-Hameete include Erasmus University Rotterdam & Erasmus University Medical Center.
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Journal ArticleDOI
The expanded clinical spectrum of anti-GABABR encephalitis and added value of KCTD16 autoantibodies.
Marleen H. van Coevorden-Hameete,Marleen H. van Coevorden-Hameete,Marienke A.A.M. de Bruijn,Esther de Graaff,Danielle A E M Bastiaansen,Marco W.J. Schreurs,Jeroen Demmers,Melanie Ramberger,Esther Hulsenboom,Mariska M.P. Nagtzaam,Sanae Boukhrissi,Jan H. Veldink,Jan J.G.M. Verschuuren,Casper C. Hoogenraad,Peter A. E. Sillevis Smitt,Maarten J. Titulaer +15 more
TL;DR: Adding KCTD16, an auxiliary protein, to a GABABR cell-based assay improves sensitivity without loss of specificity, and while the majority of patients have epilepsy, others present with progressive dementia without seizures.
Journal ArticleDOI
Detection and Characterization of Autoantibodies to Neuronal Cell-Surface Antigens in the Central Nervous System.
Marleen H. van Coevorden-Hameete,Marleen H. van Coevorden-Hameete,Maarten J. Titulaer,Marco W.J. Schreurs,Esther de Graaff,Peter A. E. Sillevis Smitt,Casper C. Hoogenraad +6 more
TL;DR: This mini-review provides a guideline for both diagnostic and research laboratories that work on the detection of known surface autoantibodies and/or the identification of novel surface antigens and is a crucial step in further disease classification and the development of novel CBAs.
Journal ArticleDOI
Antibodies to TRIM46 are associated with paraneoplastic neurological syndromes.
Marleen H. van Coevorden-Hameete,Marleen H. van Coevorden-Hameete,Sam F.B. van Beuningen,Matthieu Paul Perrenoud,Lena Will,Esther Hulsenboom,Jean-François Démonet,Lidia Sabater,Johan M. Kros,Jan J.G.M. Verschuuren,Maarten J. Titulaer,Esther de Graaff,Peter A. E. Sillevis Smitt,Casper C. Hoogenraad +13 more
TL;DR: It is shown that anti‐TRIM46 antibodies are easy to detect in routine immunohistochemistry screening and can be confirmed by western blotting and cell‐based assay.
Journal ArticleDOI
Standardized test for anti-Tr/DNER in patients with paraneoplastic cerebellar degeneration
Christian Probst,Lars Komorowski,Esther de Graaff,Marleen H. van Coevorden-Hameete,Véronique Rogemond,Jérôme Honnorat,Lidia Sabeter,Francesc Graus,Sven Jarius,Raymond Voltz,Brigitte Wildemann,Diego Franciotta,Inga Blöcker,Wolfgang Schlumberger,Winfried Stöcker,Peter A. E. Sillevis Smitt +15 more
TL;DR: This study provides Class II evidence that RC-IFA accurately detects anti-Tr as compared to conventional IFA and performs better than a frequently used commercial tissue-based indirect immunofluorescence assay (IFA) in samples with low-titer antibodies.
Journal ArticleDOI
Solubilization of human cells by the styrene-maleic acid copolymer: Insights from fluorescence microscopy.
TL;DR: The results support the general applicability of SMA for the isolation of membrane proteins from different types of (sub)cellular membranes and some plasma membrane-localized proteins were more resistant against solubilization than others.