M
Marshall P. Thomas
Researcher at Boston Children's Hospital
Publications - 14
Citations - 1649
Marshall P. Thomas is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: RNA & microRNA. The author has an hindex of 9, co-authored 14 publications receiving 1375 citations. Previous affiliations of Marshall P. Thomas include University of Colorado Denver & Harvard University.
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Journal ArticleDOI
Desperately seeking microRNA targets.
TL;DR: Computational and experimental approaches to the identification of miRNA-regulated genes are reviewed and bioinformatic analysis of over-represented pathways and nodes in protein-DNA interactomes formed from experimental candidate miRNA gene target lists can focus attention on biologically significant target genes.
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G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits
Nancy Kedersha,Marc D. Panas,Christopher A. Achorn,Shawn M. Lyons,Sarah Tisdale,Tyler T. Hickman,Marshall P. Thomas,Judy Lieberman,Gerald M. McInerney,Pavel Ivanov,Pavel Ivanov,Paul A. Anderson +11 more
TL;DR: Stress granule condensation of translationally arrested mRNAs requires G3BP and requires its RGG region for SGC and for interactions with 40S ribosomal subunits.
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Capture of MicroRNA–Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling
Ashish Lal,Marshall P. Thomas,Marshall P. Thomas,Gabriel Altschuler,Francisco Navarro,Francisco Navarro,Elizabeth M. O'Day,Elizabeth M. O'Day,Xiaoling Li,Carla P. Concepcion,Yoon-Chi Han,Jerome Thiery,Jerome Thiery,Danielle K. Rajani,Danielle K. Rajani,Aaron J. Deutsch,Aaron J. Deutsch,Oliver Hofmann,Andrea Ventura,Winston Hide,Judy Lieberman,Judy Lieberman +21 more
TL;DR: A simple biochemical method to isolate mRNAs with a transfected, biotinylated microRNA was used to identify direct target genes of miR-34a, a tumor suppressor gene as discussed by the authors.
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Apoptosis Triggers Specific, Rapid, and Global mRNA Decay with 3' Uridylated Intermediates Degraded by DIS3L2.
Marshall P. Thomas,Xing Liu,Jennifer Whangbo,Geoffrey McCrossan,Keri B. Sanborn,Emre Basar,Michael Walch,Judy Lieberman +7 more
TL;DR: It is shown that mRNAs, but not noncoding RNAs, are rapidly and globally degraded during apoptosis, suggesting that global mRNA decay is an overlooked hallmark of apoptosis.
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miR-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes.
R. Perdigao-Henriques,R. Perdigao-Henriques,Fabio Petrocca,Gabriel Altschuler,Marshall P. Thomas,Minh T.N. Le,Shen Mynn Tan,Winston Hide,Winston Hide,Judy Lieberman,Judy Lieberman +10 more
TL;DR: The miR-200 family promotes the epithelial state by suppressing the Zeb1/Zeb2 epithelial gene transcriptional repressors as discussed by the authors, which is known as miR200c.