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Marta Pastor

Researcher at University of the Basque Country

Publications -  19
Citations -  700

Marta Pastor is an academic researcher from University of the Basque Country. The author has contributed to research in topics: Solid lipid nanoparticle & Pseudomonas aeruginosa. The author has an hindex of 12, co-authored 19 publications receiving 568 citations.

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A novel strategy for the treatment of chronic wounds based on the topical administration of rhEGF-loaded lipid nanoparticles: In vitro bioactivity and in vivo effectiveness in healing-impaired db/db mice.

TL;DR: The in vitro experiments demonstrated that gamma sterilisation is a suitable process for the final sterilisation because no loss in activity was observed after the sterilisation process and the proliferation assays revealed that the bioactivity of the nanoformulations was even higher than that of free rhEGF.
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Pulmonary drug delivery: a review on nanocarriers for antibacterial chemotherapy

TL;DR: This review aims at gathering together the novel nanosystems for anti-infectious therapy, underlining the potential of DDSs to improve and optimize currently available antibiotic therapies in the context of lung infections.
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Sodium colistimethate loaded lipid nanocarriers for the treatment of Pseudomonas aeruginosa infections associated with cystic fibrosis

TL;DR: In vivo distribution experiment showed that nanoparticles spread homogenously through the lung and there was no migration of lipid nanoparticles to other organs, such as liver, spleen or kidneys, which appeared to be less toxic than free sodium colistimethate in cell culture.
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Killing effect of nanoencapsulated colistin sulfate on Pseudomonas aeruginosa from cystic fibrosis patients

TL;DR: Colistin nanoparticles had the same antimicrobial activity as free drug against planktonic bacteria, however, nanoencapsulated colistin was much more efficient in the eradication of biofilms than free colistins, and have to be considered as a good alternative therapeutic option to treat P. aeruginosa infections.