J
José Luis Pedraz
Researcher at University of the Basque Country
Publications - 299
Citations - 12591
José Luis Pedraz is an academic researcher from University of the Basque Country. The author has contributed to research in topics: Gene delivery & Medicine. The author has an hindex of 53, co-authored 271 publications receiving 10625 citations. Previous affiliations of José Luis Pedraz include Carlos III Health Institute.
Papers
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Journal ArticleDOI
Cell encapsulation: promise and progress.
Gorka Orive,Rosa Maria Hernandez,Alicia R. Gascón,Riccardo Calafiore,Thomas Ming Swi Chang,Paul de Vos,Gonzalo Hortelano,David Hunkeler,Igor Lacík,A. M. James Shapiro,José Luis Pedraz +10 more
TL;DR: This commentary discusses the reasons for this, summarizes recent progress in the field and outlines what is needed to bring this technology closer to clinical application.
Journal ArticleDOI
Biomaterials for promoting brain protection, repair and regeneration.
TL;DR: Biomaterials are likely to have an increasingly important role in the treatment of nervous system disorders because nanotechnology allows greater control over material–cell interactions that induce specific developmental processes and cellular responses including differentiation, migration and outgrowth.
Journal ArticleDOI
History, challenges and perspectives of cell microencapsulation
Gorka Orive,R.M. Hernández,Alicia R. Gascón,Riccardo Calafiore,Thomas Ming Swi Chang,Paul de Vos,Gonzalo Hortelano,David Hunkeler,Igor Lacík,José Luis Pedraz +9 more
TL;DR: This paper summarizes the current situation in the cell encapsulation field and discusses the main events that have occurred along the way, including capsule manufacture, properties and performance.
Journal ArticleDOI
Biocompatibility of alginate-poly-L-lysine microcapsules for cell therapy.
TL;DR: Detailed information is provided about the principal factors affecting the biocompatibility of alginates and alginate-poly-l-lysine microcapsules, which are the most frequently employed biomaterials and encapsulation devices for cell immobilization, respectively.
Journal ArticleDOI
Cell microencapsulation technology: towards clinical application.
Ainhoa Murua,Aitziber Portero,Gorka Orive,Rosa Ma Hernández,María de Castro,José Luis Pedraz +5 more
TL;DR: The most important advantages of this type of "living" drug release strategy are highlighted, but also its limitations pointed out, and the major challenges to be addressed in the forthcoming years are described.