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Martha Sue Carraway
Researcher at Duke University
Publications - 62
Citations - 5590
Martha Sue Carraway is an academic researcher from Duke University. The author has contributed to research in topics: Mitochondrial biogenesis & Mitochondrion. The author has an hindex of 37, co-authored 61 publications receiving 5141 citations. Previous affiliations of Martha Sue Carraway include Novo Nordisk & United States Department of Veterans Affairs.
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Journal ArticleDOI
Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1
TL;DR: Findings consign HO-1/CO signaling through Nrf2 and Akt to the myocardial transcriptional program for mitochondrial biogenesis, provide a rationale for targeted mitochondrial CO therapy, and connect cardiac mitochondrial volume expansion with the inducible network of xenobiotic and antioxidant cellular defenses.
Journal ArticleDOI
Nitric oxide in the human respiratory cycle.
Timothy J. McMahon,Richard E. Moon,Ben P. Luschinger,Martha Sue Carraway,Anne E. Stone,BW Stolp,Andrew J. Gow,John R. Pawloski,Paula L Watke,David J. Singel,Claude A. Piantadosi,Jonathan S. Stamler +11 more
TL;DR: In this paper, it was shown that in in vitro and ex vivo systems as well as healthy adults alternately exposed to hypoxia or hyperoxia (to dilate or constrict pulmonary and systemic arteries in vivo), binding of NO to hemes (FeNO) and thiols (SNO) of hemoglobin (Hb) varies as a function of oxygen tension (pO2) saturation (FeO(2) over a wide range.
Journal ArticleDOI
Composition of air pollution particles and oxidative stress in cells, tissues, and living systems.
TL;DR: Oxidative stress following PM exposure initiates a series of cellular reactions that includes activation of kinase cascades and transcription factors and release of inflammatory mediators, which ultimately lead to cell injury or apoptosis.
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Peat Bog Wildfire Smoke Exposure in Rural North Carolina Is Associated with Cardiopulmonary Emergency Department Visits Assessed through Syndromic Surveillance
Ana G. Rappold,Susan L. Stone,Wayne E. Cascio,Lucas M. Neas,Vasu Kilaru,Martha Sue Carraway,James Szykman,Amy Ising,William E. Cleve,John T. Meredith,Heather Vaughan-Batten,Lana Deyneka,Robert B. Devlin +12 more
TL;DR: This is the first study to demonstrate both respiratory and cardiac effects after brief exposure to peat wildfire smoke in rural counties with sparse air-quality monitoring.
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Lipopolysaccharide induces oxidative cardiac mitochondrial damage and biogenesis
TL;DR: These novel findings disclose a duality of reactive oxygen species (ROS) effect in the heart's response to LPS in which oxidative mitochondrial damage is opposed by oxidant stimulation of biogenesis.