M
Martin B. Powell
Researcher at University of Wales
Publications - 3
Citations - 691
Martin B. Powell is an academic researcher from University of Wales. The author has contributed to research in topics: Transgene & Gene delivery. The author has an hindex of 2, co-authored 3 publications receiving 650 citations.
Papers
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Journal ArticleDOI
Surface Expression of HLA-E, an Inhibitor of Natural Killer Cells, Enhanced by Human Cytomegalovirus gpUL40
Peter Tomasec,Veronique M. Braud,Carole R. Rickards,Martin B. Powell,Brian P. McSharry,Stephan D. Gadola,Vincenzo Cerundolo,Leszek K. Borysiewicz,Andrew J. McMichael,Gavin William Grahame Wilkinson +9 more
TL;DR: It is shown that, independently of the transporter associated with antigen processing, gpUL40 can up-regulate expression of HLA-E, which protects targets from NK cell lysis, which is up-regulated by HCMV.
Journal ArticleDOI
The reticulocalbin gene maps to the WAGR region in human and to the Small eye Harwell deletion in mouse.
Jill Kent,Muriel Lee,Andreas Schedl,Shelagh Boyle,J. Fantes,Martin B. Powell,N. K. Rushmere,Catherine M. Abbott,Veronica van Heyningen,Wendy A. Bickmore +9 more
TL;DR: The localization of the gene encoding reticulocalbin, a Ca2+-binding protein of the endoplasmic reticulum, is described and shows that it is hemizygously deleted in WAGR individuals.
Book ChapterDOI
Adenovirus cancer gene therapy
TL;DR: Recombinant adenoviruses are now used extensively in experimental protocols for the treatment of infectious, genetic and neoplastic disease with an increasing number of studies exploring the potential additive or synergistic benefits of combining multiple transgenes.