Mary E. Tokarz

TL;DR: The results suggest that an ATM kinase inhibitor may be an effective radiosensitizer and adjuvant therapy for patients with mutant p53 brain cancers.

TL;DR: The effects of initial exposure to Δ9-THC may not be entirely predictive of the effects of repeated exposure, and adolescents and adults may exhibit differences in the pattern of transition from use to abuse.

TL;DR: It is shown that Rai1 dosage has major consequences on molecular processes involved in growth, development, and neurological and behavioral functions, thus providing evidence for several dosage-thresholds for phenotypic manifestations causing dup(17)(p11.2) syndrome or SMS in humans.

TL;DR: It is demonstrated that exposure to abuse patterns of high concentrations of toluene through inhalation can alter spontaneous locomotor behavior in rats and that the expression of these effects appears to depend upon the postnatal age of testing and sex of the animal.

TL;DR: Overall, the present data indicated that failure to exhibit place preference or place aversion when tested in a drug-free state does not imply the failure of conditioning procedure; and effects of the morphine cue reinstatement during the post-conditioning tests appeared to be related to the unique pharmacological profile ofThe morphine stimulus.