M
M. Jerry Wright
Researcher at Virginia Commonwealth University
Publications - 5
Citations - 176
M. Jerry Wright is an academic researcher from Virginia Commonwealth University. The author has contributed to research in topics: Cannabinoid receptor & Nicotinic agonist. The author has an hindex of 5, co-authored 5 publications receiving 159 citations.
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Pharmacological effects of acute and repeated administration of Delta(9)-tetrahydrocannabinol in adolescent and adult rats.
TL;DR: The effects of initial exposure to Δ9-THC may not be entirely predictive of the effects of repeated exposure, and adolescents and adults may exhibit differences in the pattern of transition from use to abuse.
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Decreased sensitivity in adolescent vs. adult rats to the locomotor activating effects of toluene.
TL;DR: It is demonstrated that exposure to abuse patterns of high concentrations of toluene through inhalation can alter spontaneous locomotor behavior in rats and that the expression of these effects appears to depend upon the postnatal age of testing and sex of the animal.
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Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents
Jenny L. Wiley,Jenny L. Wiley,D. Matthew Walentiny,M. Jerry Wright,Patrick M. Beardsley,James J. Burston,Justin L. Poklis,Aron H. Lichtman,Robert E. Vann +8 more
TL;DR: The present results highlight the complex interplay between anandamide and 2-AG and suggest that endogenous increases of both endocannabinoids are most effective in elicitation of THC-like discriminative stimulus effects.
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Comparative Effects of Dextromethorphan and Dextrorphan on Nicotine Discrimination in Rats
TL;DR: The results suggest that alpha3beta4* nicotinic receptors do not play a major role in nicotine's discriminative stimulus effects and suggest that the role of cholinergic mediation of the behavioral effects of dextrorphan and dextromethorphan related to the abuse properties of nicotine may be minimal.
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Exposure to a high-fat diet decreases sensitivity to Δ9-tetrahydrocannabinol-induced motor effects in female rats.
TL;DR: The results suggest that dietary fat content may represent an important consideration in predicting the effects of marijuana in females and that pharmacokinetic differences cannot fully account for the results of the high-fat diet on response to Δ(9)-THC.