M
Marybeth A. Pysz
Researcher at Stanford University
Publications - 43
Citations - 2678
Marybeth A. Pysz is an academic researcher from Stanford University. The author has contributed to research in topics: Cancer & Cyclin D1. The author has an hindex of 25, co-authored 40 publications receiving 2367 citations. Previous affiliations of Marybeth A. Pysz include North Carolina State University & University of California, San Francisco.
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Journal ArticleDOI
Protein Kinase C α Signaling Inhibits Cyclin D1 Translation in Intestinal Epithelial Cells
TL;DR: The mechanisms underlying PKCα-induced loss of cyclin D1 protein in non-transformed intestinal epithelial cells are explored, and PKC α is identified as a novel repressor of cyclIn D1 translation, acting at the level of cap-dependent initiation.
Journal ArticleDOI
PKCα tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1
Marybeth A. Pysz,Olga V. Leontieva,Nicholas W. Bateman,Joshua M. Uronis,Kathryn J. Curry,David W. Threadgill,Klaus-Peter Janssen,Sylvie Robine,Anna Velcich,Leonard H. Augenlicht,Adrian R. Black,Jennifer D. Black +11 more
TL;DR: In this article, the effects of restoring PKCα or PKCδ isozyme expression on cyclin D1 were investigated in colon cancer cells, and it was shown that PKCβII was elevated and PKC∆ showed variable expression.
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Initiation and characterization of small cell lung cancer patient-derived xenografts from ultrasound-guided transbronchial needle aspirates.
Wade C. Anderson,Michael Boyd,Jorge Aguilar,Brett Pickell,Amy Laysang,Marybeth A. Pysz,Sheila Bheddah,Johanna Ramoth,Brian Slingerland,Scott J. Dylla,Edmundo Rubio +10 more
TL;DR: It is demonstrated that PDX tumor models can be efficiently established from primary SCLC transbronchial needle aspirates, even after overnight shipping, and that resulting xenograft tumors are similar to matched primary tumors in cancer patients by both histology and chemo-sensitivity.
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Fast microbubble dwell-time based ultrasonic molecular imaging approach for quantification and monitoring of angiogenesis in cancer.
TL;DR: Fast ultrasonic molecular imaging based on dwell time microbubble signal measurements correlates well with the traditional measurement method, and allows reliable in vivo monitoring of anti-angiogenic therapy in human colon cancer xenografts.
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Quantitative assessment of tumor angiogenesis using real-time motion-compensated contrast-enhanced ultrasound imaging
TL;DR: Real-time motion-compensated MIP ultrasound imaging allows reliable and accurate quantification and monitoring of angiogenesis in tumors exposed to breathing-induced motion artifacts.