M
Marzieh Najafi
Researcher at Utrecht University
Publications - 7
Citations - 90
Marzieh Najafi is an academic researcher from Utrecht University. The author has contributed to research in topics: Micelle & Atom-transfer radical-polymerization. The author has an hindex of 5, co-authored 7 publications receiving 64 citations.
Papers
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Journal ArticleDOI
Native Chemical Ligation for Cross-Linking of Flower-Like Micelles.
Marzieh Najafi,Neda Kordalivand,Mohammad Amin Moradi,Joep van den Dikkenberg,Remco Fokkink,Heiner Friedrich,Nico A. J. M. Sommerdijk,Mathew Hembury,Tina Vermonden +8 more
TL;DR: In this paper, native chemical ligation (NCL) was used as a selective cross-linking method to form core-crosslinked thermosensitive polymeric micelles for drug delivery applications.
Journal ArticleDOI
Conversion of an Injectable MMP-Degradable Hydrogel into Core-Cross-Linked Micelles.
Marzieh Najafi,Hamed Asadi,Hamed Asadi,Joep van den Dikkenberg,Mies J. van Steenbergen,Marcel H.A.M. Fens,Wim E. Hennink,Tina Vermonden +7 more
TL;DR: A new type of injectable hydrogel called “HyMic” that can convert into core cross-linked (CCL) micelles upon exposure to matrix metalloproteinases (MMP’s), was designed and developed for drug delivery applications.
Journal ArticleDOI
Inhibition of Octreotide Acylation Inside PLGA Microspheres by Derivatization of the Amines of the Peptide with a Self-Immolative Protecting Group
Mehrnoosh Shirangi,Marzieh Najafi,Dirk T. S. Rijkers,Robbert J. Kok,Wim E. Hennink,Cornelus F. van Nostrum +5 more
TL;DR: The incorporation of self-immolative protection groups provides a viable approach for inhibition of acylation of peptides in PLGA delivery systems.
Book ChapterDOI
Poly(N‐isopropylacrylamide): Physicochemical Properties and Biomedical Applications
TL;DR: In this article, an overview of the most frequently used polymerization techniques (free and living radical polymerization) is given, and a variety of copolymers and structures obtained by these methods are highlighted.
Journal ArticleDOI
Heterofunctional Poly(ethylene glycol) (PEG) Macroinitiator Enabling Controlled Synthesis of ABC Triblock Copolymers
TL;DR: This novel PEG macroinitiator allows the development of elegant synthesis routes for PEG midblock-containing ABC copolymers that does not require protection of initiating sites or polymer end-group postmodification.