Masakazu Miura

TL;DR: The results suggest that cerebrospinal fluid tau might reflect the progressive accumulation of altered tau due to the progressive death of neurons in the AD brain, and that the enzyme‐linked immunosorbent assay of cerebro Spinal Fluid tau may prove to be a reliable and early diagnostic test for AD.

TL;DR: Community-dwelling elderly people aged ≥66 years who participated in the present study underwent brain MRI and standardized physical and neuropsychological examinations as well as blood biochemistry determinations, and pHcy level is associated with age and nutritional and other lifestyle factors, and it contributes to a risk for Silent brain infarction.

TL;DR: This study suggests that tau may accumulate in the CSF of patients with certain neurodegenerative diseases other than AD and that measurement of CSF-tau may not distinguish AD from DLB.

TL;DR: It is suggested that VD constitutes a group of dementias that can be separated from AD by normal CSF-tau levels, and CSF/ml determinations in combination with other clinical findings may provide another diagnostic aid in the differential diagnosis between VD and AD.

TL;DR: It is suggested that alcohol-induced organic brain disorders are a group of dementias that are characterized by normal CSF-tau levels, and that the CSF examination for tau in combination with other clinical findings may help in differentiating alcohol- induced Organic brain disorders from AD.