M
Masakazu Umezawa
Researcher at Tokyo University of Science
Publications - 105
Citations - 2048
Masakazu Umezawa is an academic researcher from Tokyo University of Science. The author has contributed to research in topics: Chemistry & Offspring. The author has an hindex of 20, co-authored 87 publications receiving 1443 citations.
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Journal ArticleDOI
Maternal exposure to nanoparticulate titanium dioxide during the prenatal period alters gene expression related to brain development in the mouse
TL;DR: Investigating the effects of maternal exposure to nano-sized anatase titanium dioxide (TiO2) on gene expression in the brain during the developmental period using cDNA microarray analysis combined with Gene Ontology (GO) and Medical Subject Headings (MeSH) terms information indicated that expression levels of genes associated with apoptosis and those associated with brain development were altered in newborn pups.
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Particle toxicology and health - where are we?
Michael Riediker,Daniele Zink,Wolfgang G. Kreyling,Günter Oberdörster,Alison Elder,Uschi M. Graham,Iseult Lynch,Albert Duschl,Gaku Ichihara,Sahoko Ichihara,Takahiro Kobayashi,Naomi Hisanaga,Masakazu Umezawa,Tsun-Jen Cheng,Richard D. Handy,Mary Gulumian,Sally S. Tinkle,Flemming R. Cassee +17 more
TL;DR: Lessons learned from the past can prove helpful for the future of the field, notably for understanding novel particles and fibres and for defining appropriate risk management and governance approaches.
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In utero exposure to a low concentration of diesel exhaust affects spontaneous locomotor activity and monoaminergic system in male mice
Tomoharu Suzuki,Tomoharu Suzuki,Shigeru Oshio,Shigeru Oshio,Mari Iwata,Hisayo Saburi,Takashi Odagiri,Tadashi Udagawa,Isamu Sugawara,Masakazu Umezawa,Ken Takeda +10 more
TL;DR: Exposure of mice in utero to a low concentration of diesel exhaust decreases SLA and alters the neurochemical monoamine metabolism of several regions of the brain, including the striatum, in the exposure group.
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Ratiometric near-infrared fluorescence nanothermometry in the OTN-NIR (NIR II/III) biological window based on rare-earth doped β-NaYF4 nanoparticles
TL;DR: A novel nanothermometer based on over-1000 nm (OTN) near-infrared (NIR) emission of rare-earth doped ceramic nanophosphors (RED-CNPs) was developed for temperature measurement in deep tissue and the obtained NaYF4:Yb3+,Ho3+,Er3+ NPs are promising as a novel fluorescent nanotherMometer for deep tissue.
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Exposure to diesel exhaust during fetal period affects behavior and neurotransmitters in male offspring mice.
TL;DR: The study found that prenatal exposure to DE alters motor coordination, impulsive behavior and related monoamine levels and high performance liquid chromatography analysis revealed that noradrenaline turnover in the cerebellum was decreased, and was significantly increased in the hypothalamus.