M
Masanao Ogawa
Researcher at National Institute of Radiological Sciences
Publications - 77
Citations - 1316
Masanao Ogawa is an academic researcher from National Institute of Radiological Sciences. The author has contributed to research in topics: Radiosynthesis & Chemistry. The author has an hindex of 19, co-authored 66 publications receiving 1128 citations.
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Journal ArticleDOI
Development of a new radioligand, N-(5-fluoro-2-phenoxyphenyl)-N-(2-[18F]fluoroethyl-5-methoxybenzyl)acetamide, for pet imaging of peripheral benzodiazepine receptor in primate brain.
Ming-Rong Zhang,Jun Maeda,Masanao Ogawa,Junko Noguchi,Takehito Ito,Yuichiro Yoshida,Takashi Okauchi,Shigeru Obayashi,Tetsuya Suhara,Kazutoshi Suzuki +9 more
TL;DR: The biological data indicate that [(18)F]5 is a useful PET ligand for PBR and is currently used for imaging PBR in human brain.
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[18F]FMDAA1106 and [18F]FEDAA1106: two positron-emitter labeled ligands for peripheral benzodiazepine receptor (PBR).
Ming-Rong Zhang,Jun Maeda,Kenji Furutsuka,Yuichiro Yoshida,Masanao Ogawa,Tetsuya Suhara,Kazutoshi Suzuki +6 more
TL;DR: Ex vivo autoradiograms of ex vivo binding sites in the rat brains revealed that a high radioactivity was present in the olfactory bulb, the highest PBR density region in the brain.
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PET imaging of lung inflammation with [18F]FEDAC, a radioligand for translocator protein (18 kDa).
Akiko Hatori,Joji Yui,Tomoteru Yamasaki,Lin Xie,Katsushi Kumata,Masayuki Fujinaga,Yuichiro Yoshida,Masanao Ogawa,Nobuki Nengaki,Kazunori Kawamura,Toshimitsu Fukumura,Ming-Rong Zhang +11 more
TL;DR: It is concluded that PET with [18F]FEDAC may be a useful tool for imaging TSPO expression and evaluating progress of lung inflammation.
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In vivo binding properties of [carbonyl-11C]WAY-100635: effect of endogenous serotonin.
Jun Maeda,Tetsuya Suhara,Masanao Ogawa,Takashi Okauchi,Kouichi Kawabe,Ming-Rong Zhang,Jun'Ichi Semba,Kazutoshi Suzuki +7 more
TL;DR: Results indicated that the in vivo binding of [carbonyl‐11C]WAY‐100635 in the hippocampus and cerebral cortex mainly reflects postsynaptic 5‐HT1A receptor binding, and that this binding is not sensitive to endogenous 5‐ HT.
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[11C]sorafenib: radiosynthesis and preliminary PET study of brain uptake in P-gp/Bcrp knockout mice.
Chiharu Asakawa,Masanao Ogawa,Katsushi Kumata,Masayuki Fujinaga,Koichi Kato,Tomoteru Yamasaki,Joji Yui,Kazunori Kawamura,Akiko Hatori,Toshimitsu Fukumura,Ming-Rong Zhang +10 more
TL;DR: Developed and evaluated the influence of ABC transporters-mediated efflux on brain uptake using PET with [(11)C]1, and indicated that the radioactivity level in the brains of P-gp/Bcrp knockout mice was about three times higher than in wild-type mice.