T
Tetsuya Suhara
Researcher at National Institute of Radiological Sciences
Publications - 470
Citations - 22173
Tetsuya Suhara is an academic researcher from National Institute of Radiological Sciences. The author has contributed to research in topics: Dopamine & Dopaminergic. The author has an hindex of 72, co-authored 457 publications receiving 19946 citations. Previous affiliations of Tetsuya Suhara include Keio University & Tohoku University.
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Journal ArticleDOI
Consensus nomenclature for in vivo imaging of reversibly binding radioligands
Robert B. Innis,Vincent J. Cunningham,Jacques Delforge,Masahiro Fujita,Albert Gjedde,Roger N. Gunn,James E. Holden,Sylvain Houle,Sung-Cheng Huang,Masanori Ichise,Hidehiro Iida,Hiroshi Ito,Yuichi Kimura,Robert A. Koeppe,Gitte M. Knudsen,Juhani Knuuti,Adriaan A. Lammertsma,Marc Laruelle,Jean Logan,Ralph Paul Maguire,Mark A. Mintun,Evan D. Morris,Ramin V. Parsey,Julie C. Price,Mark Slifstein,Vesna Sossi,Tetsuya Suhara,John R. Votaw,Dean F. Wong,Richard E. Carson +29 more
TL;DR: An international group of experts in pharmacokinetic modeling recommends a consensus nomenclature to describe in vivo molecular imaging of reversibly binding radioligands.
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Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model
Yasumasa Yoshiyama,Makoto Higuchi,Bin Zhang,Shu-Ming Huang,Nobuhisa Iwata,Takaomi C. Saido,Jun Maeda,Tetsuya Suhara,John Q. Trojanowski,Virginia M.-Y. Lee +9 more
TL;DR: In this paper, the authors studied wild-type and P301S mutant human tau transgenic (Tg) mice and found that tangle formation was preceded by microglial activation.
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Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET
Yoshiro Okubo,Yoshiro Okubo,Tetsuya Suhara,Kazutoshi Suzuki,Kaoru Kobayashi,Osamu Inoue,Omi Terasaki,Omi Terasaki,Yasuhiro Someya,Yasuhiro Someya,Takeshi Sassa,Takeshi Sassa,Yasuhiko Sudo,Eisuke Matsushima,Masaomi Iyo,Yukio Tateno,Michio Toru +16 more
TL;DR: Although no differences were observed in the striatum relative to control subjects, binding of radioligand to D1R was reduced in the prefrontal cortex of schizophrenics, and this reduction was related to the severity of the negative symptoms and to poor performance in the Wisconsin Card Sorting Test.
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Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls
Masahiro Maruyama,Hitoshi Shimada,Tetsuya Suhara,Hitoshi Shinotoh,Bin Ji,Jun Maeda,Ming-Rong Zhang,John Q. Trojanowski,Virginia M.-Y. Lee,Maiko Ono,Kazuto Masamoto,Harumasa Takano,Naruhiko Sahara,Naruhiko Sahara,Nobuhisa Iwata,Nobuyuki Okamura,Shozo Furumoto,Yukitsuka Kudo,Qing Chang,Takaomi C. Saido,Akihiko Takashima,Jada Lewis,Ming Kuei Jang,Ichio Aoki,Hiroshi Ito,Makoto Higuchi +25 more
TL;DR: A class of tau ligands, phenyl/pyridinyl-butadienyl-benzothiazoles/benZothiazoliums (PBBs), for visualizing diverse tau inclusions in brains of living patients with AD or non-AD tauopathies and animal models of these disorders are developed.
Journal ArticleDOI
Linearized Reference Tissue Parametric Imaging Methods: Application to [11C]DASB Positron Emission Tomography Studies of the Serotonin Transporter in Human Brain:
Masanori Ichise,Jeih-San Liow,Jian Qiang Lu,Akihiro Takano,Kendra Model,Hiroshi Toyama,Tetsuya Suhara,Kazutoshi Suzuki,Robert B. Innis,Richard E. Carson +9 more
TL;DR: Rapid parametric imaging by MRTM2 should be a useful method for human [11C]DASB positron emission tomography studies as it allowed rapid generation of parametric images with the noise reductions consistent with the simulations.