M
Masanori Suzuki
Researcher at Tohoku University
Publications - 80
Citations - 2562
Masanori Suzuki is an academic researcher from Tohoku University. The author has contributed to research in topics: Antigen & Organic anion transporter 1. The author has an hindex of 22, co-authored 80 publications receiving 2479 citations.
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Journal ArticleDOI
Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1.
Takaaki Abe,Masayuki Kakyo,Taro Tokui,Rie Nakagomi,Toshiyuki Nishio,Daisuke Nakai,Hideki Nomura,Michiaki Unno,Masanori Suzuki,Takeshi Naitoh,Seiki Matsuno,Hiromu Yawo +11 more
TL;DR: This is the first report of the human molecule that transports thyroid hormones, and probably the most important transporter in human liver for clearance of bile acids and organic anions because hepatic levels of another organic anion transporter, OATP, is very low.
Journal ArticleDOI
LST-2, A human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers
Takaaki Abe,Michiaki Unno,Tohru Onogawa,Taro Tokui,Tohru Noriko Kondo,Rie Nakagomi,Hisanobu Adachi,Koh Fujiwara,Mitsunori Okabe,Takehiro Suzuki,Kazuo Nunoki,Eiichi Sato,Masayuki Kakyo,Toshiyuki Nishio,Junichi Sugita,Naoki Asano,Masayuki Tanemoto,Makoto Seki,Fumiko Date,Katsuhiko Ono,Yoshiaki Kondo,Kenichi Shiiba,Masanori Suzuki,Haruo Ohtani,Tooru Shimosegawa,Kazuie Iinuma,Hiroshi Nagura,Sadayoshi Ito,Seiki Matsuno +28 more
TL;DR: LST-2 is one of the prime candidate molecules for determining methotrexate sensitivity and may be a good target to deliver anticancer drugs to the gastrointestinal cancers.
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Identification of thyroid hormone transporters in humans: different molecules are involved in a tissue-specific manner.
Koh Fujiwara,Hisanobu Adachi,Toshiyuki Nishio,Michiaki Unno,Taro Tokui,Mitsunori Okabe,Tohru Onogawa,Takehiro Suzuki,Naoki Asano,Masayuki Tanemoto,Makoto Seki,Kenichi Shiiba,Masanori Suzuki,Yoshiaki Kondo,Kazuo Nunoki,Tooru Shimosegawa,Kazuie Iinuma,Sadayoshi Ito,Seiki Matsuno,Takaaki Abe +19 more
TL;DR: Homology analysis and the phylogenetic tree analysis revealed that OATP-E/oatp-E is a subfamily of the organic anion transporter, and the clone was isolated from the brain and messenger RNA was abundantly expressed in various peripheral tissues.
Journal ArticleDOI
Establishment of a New Extrahepatic Bile Duct Carcinoma Cell Line, TFK-1
Susumu Saijyo,Toshio Kudo,Masanori Suzuki,Yu Katayose,Masao Shinoda,Taisei Muto,Kenji Fukuhara,Takao Suzuki,Seiki Matsuno +8 more
TL;DR: TFK-1 is the third cell line established from extrahepatic bile duct carcinomas in the world literature, and should provide useful information on various aspects of this type of neoplasm.
Journal ArticleDOI
Molecular characterization and functional regulation of a novel rat liver-specific organic anion transporter rlst-1
Masayuki Kakyo,Michiaki Unno,Taro Tokui,Rie Nakagomi,Toshiyuki Nishio,Hajime Iwasashi,Daisuke Nakai,Makoto Seki,Masanori Suzuki,Takeshi Naitoh,Seiki Matsuno,Hiromu Yawo,Takaaki Abe +12 more
TL;DR: In this article, a rat liver cDNA library was screened with human liver-specific organic anion transporter (LST-1) cDNA as a probe, and the expression regulation of its mRNA was examined to clarify the molecular basis of cholestasis.